The human brain undergoes marked structural changes with age including cortical thinning
and reduced connectivity because of the degradation of myelin. Although these changes …

Physical activity has been shown to benefit brain and cognition in late adulthood. However,
this effect is still unexplored in terms of brain signal complexity, which reflects the level of …

Abstract The Compensation Related Utilization of Neural Circuits Hypothesis (CRUNCH)
proposes a framework for understanding task-related brain activity changes as a function of …

The dynamics of the resting-state activity in brain functional networks are complex,
containing meaningful patterns over multiple temporal scales. Such physiologic complexity …

Aging is associated with changes in brain structure and function with some brain regions
showing more age-related deterioration than others. There is evidence that regional …

Brain complexity, which reflects the ability of the brain to adapt to a changing environment,
has been found to be significantly changed with age. However, there is less evidence on the …

Physical inactivity has been identified as an important risk factor for dementia. High levels of
cardiorespiratory fitness (CRF) have been shown to reduce the risk of dementia. However …

Aging reduces cognitive functions, and such impairments have implications in mental and
motor performance. Cognitive function has been recently linked to the risk of falls in older …

The extent of task-related fMRI activation can vary as a function of task difficulty. Also the
efficiency or capacity of the brain networks underlying task performance can change with …

Brain organization can be measured across multiple spatial and temporal scales where
each scale affects the other in the emergent functions that are known as cognition. As a …