CRISPR is becoming an indispensable tool in biological research. Once known as the
bacterial immune system against invading viruses, the programmable capacity of the Cas9 …

The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR (clustered
regularly interspaced short palindromic repeats) bacterial immune systems, is emerging as a …

Advances in the development of delivery, repair, and specificity strategies for the CRISPR-
Cas9 genome engineering toolbox are helping researchers understand gene function with …

The prokaryote-derived CRISPR–Cas genome editing systems have transformed our ability
to manipulate, detect, image and annotate specific DNA and RNA sequences in living cells …

Ease of use, economy and speed of targeting DNA has propelled the CRISPR-Cas system
into the spotlight. Now, despite numerous gaps in our knowledge, commercial entities are …

The ability to add, remove, or change DNA sequences is essential to studies that investigate
the genetic underpinning of phenotypic traits. With its unprecedented efficiency and stunning …

Recently, a novel technique named the clustered regularly interspaced short palindromic
repeat (CRISPR)/CRISPR‐associated protein (Cas) 9 system has been rapidly developed …

ABSTRACT CRISPR (Clustered Regularly-Interspaced Short Palindromic Repeats)-Cas9
(CRISPR associated protein 9) has rapidly become the most promising genome editing tool …

The type-V CRISPR effector Cas12b (formerly known as C2c1) has been challenging to
develop for genome editing in human cells, at least in part due to the high temperature …

With the expansion of the microbiology field of research, a new genome editing tool arises
from the biology of bacteria that holds the promise of achieving precise modifications in the …