[HTML][HTML] Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and …
Y Wang, M Liu, Y Shen, Y Ma, X Li, Y Zhang, M Liu… - Cell Discovery, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
of concern, including Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2) …
of concern, including Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2) …
Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease …
of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease …
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice
Severe acute respiratory syndrome coronaviruses 1 (SARS-CoV) and 2 (SARS-CoV-2),
including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality …
including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality …
[PDF][PDF] Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain
Y Wang, Z Zhang, M Yang, X Xiong, Q Yan, L Cao… - Cell Reports, 2024 - cell.com
Omicron, as the emerging variant with enhanced vaccine tolerance, has sharply disrupted
most therapeutic antibodies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
most therapeutic antibodies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
[PDF][PDF] Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
Many anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) neutralizing
antibodies target the angiotensin-converting enzyme 2 (ACE2) binding site on viral spike …
antibodies target the angiotensin-converting enzyme 2 (ACE2) binding site on viral spike …
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine
The rapid emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants that evade immunity elicited by vaccination has placed an imperative on the …
variants that evade immunity elicited by vaccination has placed an imperative on the …
[HTML][HTML] Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants
T Li, W Xue, Q Zheng, S Song, C Yang, H Xiong… - Nature …, 2021 - nature.com
The emergence of numerous variants of SARS-CoV-2, the causative agent of COVID-19,
has presented new challenges to the global efforts to control the COVID-19 pandemic. Here …
has presented new challenges to the global efforts to control the COVID-19 pandemic. Here …
[HTML][HTML] A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice
Abstract SARS-CoV in 2003, SARS-CoV-2 in 2019, and SARS-CoV-2 variants of concern
(VOC) can cause deadly infections, underlining the importance of developing broadly …
(VOC) can cause deadly infections, underlining the importance of developing broadly …
[HTML][HTML] Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody
MA Tortorici, N Czudnochowski, TN Starr, R Marzi… - bioRxiv, 2021 - ncbi.nlm.nih.gov
The recent emergence of SARS-CoV-2 variants of concern (VOC) and the recurrent
spillovers of coronaviruses in the human population highlight the need for broadly …
spillovers of coronaviruses in the human population highlight the need for broadly …
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
SARS-CoV-2 is a newly emerged coronavirus responsible for the current COVID-19
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …