Natriuretic peptides: biochemistry, physiology, and therapeutic role in heart failure.

G Stoupakis, M Klapholz - Heart disease (Hagerstown, Md.), 2003 - europepmc.org
Cardiac natriuretic peptides are a family of structurally related peptides that are important in
sodium and volume homeostasis. They consist of atrial natriuretic peptide, brain natriuretic …

Heart failure phenotypes according to natriuretic peptide trajectory following initiation of sacubitril/valsartan

R Mohebi, Y Liu, PL Myhre, GM Felker, MF Prescott… - Heart Failure, 2023 - jacc.org
When measured in ambulatory individuals with heart failure (HF), higher concentrations of N-
terminal pro–B-type natriuretic peptide (NT-proBNP) have been linked with HF severity and …

[HTML][HTML] Current understanding of the compensatory actions of cardiac natriuretic peptides in cardiac failure: a clinical perspective

NS Lee, LB Daniels - Cardiac failure review, 2016 - ncbi.nlm.nih.gov
Natriuretic peptides play a crucial role in maintaining cardiovascular homeostasis. Among
their properties are vasodilation, natriuresis, diuresis, and inhibition of cardiac remodeling …

C-type natriuretic peptide and heart failure

S Del Ry, C Passino, M Emdin, D Giannessi - Pharmacological research, 2006 - Elsevier
C-type natriuretic peptide (CNP) is a peptide produced by the vascular endothelium with
vasodilative properties. It shares structural and physiological properties with the atrial and …

The genetic contribution of the natriuretic peptide system to cardiovascular diseases

T Nakayama - Endocrine journal, 2005 - jstage.jst.go.jp
Three types of natriuretic peptides (NP) have been isolated: atrial natriuretic peptide (ANP),
brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The NP family elicits a …

Natriuretic peptides: degradation, circulating forms, dosages and new therapeutic approaches.

J Favresse, D Gruson - Annales de Biologie Clinique, 2017 - europepmc.org
Testing for natriuretic peptides (BNP, NT-proBNP or MR-proANP) is recommended by the
European Society of Cardiology (ESC) since 2005 for the exclusion diagnosis of acute and …

[HTML][HTML] Natriuretic peptide-guided therapy for heart failure: ready for “battle” or too “scarred” by the challenges of trial design?

A Maisel - Journal of the American College of Cardiology, 2009 - jacc.org
While natriuretic peptide (NP) testing has gained widespread acceptance for the diagnosis
and prognosis of heart failure (HF), as well as risk stratification across the spectrum of …

Therapeutic progress and knowledge basis on the natriuretic peptide system in heart failure

S Fu, Z Chang, L Luo, J Deng - Current Topics in Medicinal …, 2019 - ingentaconnect.com
Notwithstanding substantial improvements in diagnosis and treatment, Heart Failure (HF)
remains a major disease burden with high prevalence and poor outcomes worldwide …

[PDF][PDF] Natriuretic peptides-physiology, pathophysiology and clinical use in heart failure.

J Krupička, T Janota, Z Kasalova, J Hradec - Physiological research, 2009 - Citeseer
The natriuretic peptides–atrial, brain and C-type–were discovered during the last twenty
years. Their effects on cardiovascular, renal, cerebral and other tissues through guanylyl …

Molecular signaling mechanisms and function of natriuretic peptide receptor-A in the pathophysiology of cardiovascular homeostasis

KN Pandey - Frontiers in physiology, 2021 - frontiersin.org
The discovery of atrial, brain, and C-type natriuretic peptides (ANP, BNP, and CNP) and their
cognate receptors has greatly increased our knowledge of the control of hypertension and …