In utero exposure of mouse progeny to alcohol (ethanol, EtOH) and methamphetamine
(METH) causes substantial postnatal neurodevelopmental deficits. One emerging …

This review covers molecular mechanisms involving oxidative stress and DNA damage that
may contribute to morphological and functional developmental disorders in animal models …

The ingestion of alcohol/ethanol during pregnancy can result in abnormal fetal development
in both humans and a variety of experimental animal models. Depending on the pattern of …

The abuse of licit and illicit drugs is a worldwide issue that is a cause for concern in pregnant
women. It may lead to complications in pregnancy that may affect the mother, fetus, and/or …

Ethanol exposure during pregnancy can produce a variety of central nervous system
abnormalities in the offspring, resulting in a broad spectrum of cognitive and behavioral …

Numerous mechanisms likely contribute to the damaging effects of prenatal alcohol
exposure on the developing fetus and particularly the developing central nervous system …

Background Maternal exposure to environmental stressors poses a risk to fetal
development. Oxidative stress (OS), microglia activation, and inflammation are three tightly …

Prenatal substance exposure is a growing public health concern worldwide. Although the
opioid crisis remains one of the most prevalent addiction problems in our society, abuse of …

Studies in mice with deficient antioxidative enzymes have shown that physiological levels of
reactive oxygen species (ROS) can adversely affect the developing embryo and fetus …

Objective: To determine whether in utero tobacco and alcohol exposure induces long-term
neurobehavioral alterations and whether oxidative stress/damage is a possible causal …