nAChRs are pentameric transmembrane proteins into the superfamily of ligand-gated ion
channels that includes the 5HT3, glycine, GABAA, and GABAC receptors. Electron …

Nicotinic acetylcholine receptors (nAChRs) belong to the “Cys-loop” superfamily of ligand-
gated ion channels that includes GABA A, glycine, and serotonin (5-HT 3) receptors. There …

Nicotinic acetylcholine receptors (nAChRs) are members of an extensive super-family of
neurotransmitter-gated ion channels. In humans, nAChRs are expressed within the nervous …

The amino acid sequences of nicotinic acetylcholine receptors (nAChRs) from diverse
species can be compared across extracellular, transmembrane, and intracellular domains …

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels and can be
divided into two groups: muscle receptors, which are found at the skeletal neuromuscular …

The nAChR is a membrane-bound allosteric protein which carries several categories of
topologically distinct binding sites and mediates interactions between these sites by …

Nearly 30 years of experimental evidence supports the argument that ligands of nicotinic
acetylcholine receptors (nAChRs) have potential as therapeutic agents. However, as in the …

The potent behavioral and cognitive effects of nicotine highlight the physiological
importance of nicotinic acetylcholine receptors (nAChRs). These receptors are part of the …

Neuronal nicotinic acetylcholine receptors (nAChRs) are a heterogeneous family of
pentameric ligand-gated cation channels that are expressed throughout the brain and …

Postsynaptic nAChRs in the peripheral nervous system are critical for neuromuscular and
autonomic neurotransmission. Pre-and peri-synaptic nAChRs in the brain modulate …