[HTML][HTML] Finding essentiality feasible: common questions and misinterpretations concerning the “essential-use” concept

IT Cousins, JC De Witt, J Glüge… - … Science: Processes & …, 2021 - pubs.rsc.org
The essential-use concept is a tool that can guide the phase-out of per-and polyfluoroalkyl
substances (PFAS) and potentially other substances of concern. This concept is a novel …

Information requirements under the essential-use concept: PFAS case studies

J Glüge, R London, IT Cousins, J DeWitt… - … science & technology, 2021 - ACS Publications
Per-and polyfluoroalkyl substances (PFAS) are a class of substances for which there are
widespread concerns about their extreme persistence in combination with toxic effects. It has …

[HTML][HTML] The concept of essential use for determining when uses of PFASs can be phased out

IT Cousins, G Goldenman, D Herzke… - … Science: Processes & …, 2019 - pubs.rsc.org
Because of the extreme persistence of per-and polyfluoroalkyl substances (PFASs) and their
associated risks, the Madrid Statement argues for stopping their use where they are deemed …

[HTML][HTML] Strategies for grouping per-and polyfluoroalkyl substances (PFAS) to protect human and environmental health

IT Cousins, JC DeWitt, J Glüge, G Goldenman… - … Science: Processes & …, 2020 - pubs.rsc.org
Grouping strategies are needed for per-and polyfluoroalkyl substances (PFAS), in part,
because it would be time and resource intensive to test and evaluate the more than 4700 …

Zürich statement on future actions on per-and polyfluoroalkyl substances (PFASs)

A Ritscher, Z Wang, M Scheringer… - Environmental …, 2018 - ehp.niehs.nih.gov
Per-and polyfluoroalkyl substances (PFASs) are man-made chemicals that contain at least
one perfluoroalkyl moiety,–C n F 2 n–. To date, over 4,000 unique PFASs have been used in …

[HTML][HTML] An overview of the uses of per-and polyfluoroalkyl substances (PFAS)

J Glüge, M Scheringer, IT Cousins, JC DeWitt… - … Science: Processes & …, 2020 - pubs.rsc.org
Per-and polyfluoroalkyl substances (PFAS) are of concern because of their high persistence
(or that of their degradation products) and their impacts on human and environmental health …

Zürich II Statement on Per-and Polyfluoroalkyl Substances (PFASs): Scientific and Regulatory Needs

JC DeWitt, J Glüge, IT Cousins… - … & Technology Letters, 2024 - ACS Publications
Per-and polyfluoroalkyl substances (PFASs) are a class of synthetic organic chemicals of
global concern. A group of 36 scientists and regulators from 18 countries held a hybrid …

PFAS Experts Symposium: Statements on regulatory policy, chemistry and analytics, toxicology, transport/fate, and remediation for per‐and polyfluoroalkyl substances …

JA Simon, S Abrams, T Bradburne, D Bryant… - Remediation …, 2019 - Wiley Online Library
Sixty leading members of the scientific, engineering, regulatory, and legal communities
assembled for the PFAS Experts Symposium in Arlington, Virginia on May 20 and 21, 2019 …

Can chemical class approaches replace chemical-by-chemical strategies? Lessons from recent US FDA regulatory action on per-and polyfluoroalkyl substances

A Cordner, L Richter, P Brown - Environmental Science & …, 2016 - ACS Publications
Concern about the toxicity and exposure of per-and polyfluoroalkyl substances (PFASs) is
growing among scientists, regulators, and residents of contaminated communities. In 2016 …

[HTML][HTML] The high persistence of PFAS is sufficient for their management as a chemical class

IT Cousins, JC DeWitt, J Glüge, G Goldenman… - … Science: Processes & …, 2020 - pubs.rsc.org
Per-and polyfluoroalkyl substances (PFAS) are a class of synthetic organic substances with
diverse structures, properties, uses, bioaccumulation potentials and toxicities. Despite this …