A biomarker that will enable the identification of patients at high-risk for developing post-
injury epilepsy is critically required. Microvascular pathology and related blood–brain barrier …

Increased permeability of the blood–brain barrier (BBB) following cerebral injury results in
regional extravasation of plasma proteins and can critically contribute to the pathogenesis of …

Epilepsy has been associated with a dysfunction of the blood–brain barrier. While there is
ample evidence that a dysfunction of the blood–brain barrier contributes to epileptogenesis …

Insult-associated blood–brain barrier leakage is strongly suggested to be a key step during
epileptogenesis. In this study, we used three non-invasive translational imaging modalities …

Brain inflammation, angiogenesis and increased blood-brain barrier (BBB) permeability
occur in adult rodent and human epileptogenic brain tissue. We addressed the role of these …

The blood–brain barrier (BBB) plays an important role in the homeostasis of the brain. BBB
dysfunction has been implicated in the pathophysiology of various neurological disorders …

Background Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which
typically develops within 2 years post-injury with poorly understood mechanisms. We …

Traumatic brain injury (TBI) accounts for approximately 16% of acute symptomatic seizures
which usually occur in the first week after trauma. Children are at higher risk for post …

The blood–brain barrier, a unique feature of the cerebral vasculature, is gaining attention as
a feature in common neurologic disorders including stroke, traumatic brain injury, epilepsy …

The blood–brain barrier (BBB), a unique anatomical and physiological interface between the
central nervous system (CNS) and the peripheral circulation, is essential for the function of …