Targeting NOX, INOS and COX‐2 in inflammatory cells: chemoprevention using food phytochemicals

A Murakami, H Ohigashi - International journal of cancer, 2007 - Wiley Online Library
Biological, biochemical and physical stimuli activate inflammatory leukocytes, such as
macrophages, resulting in induction and synthesis of proinflammatory proteins and …

Chemoprevention with phytochemicals targeting inducible nitric oxide synthase

A Murakami - Food Factors for Health Promotion, 2009 - karger.com
A regulated low level of nitric oxide (NO) production in the body is essential for maintaining
homeostasis (neuroprotection, vasorelaxation, etc.), though certain pathophysiological …

[PDF][PDF] NF-kappa B and Nrf2 as potential chemopreventive targets of some anti-inflammatory and antioxidative phytonutrients with anti-inflammatory and antioxidative …

YJ Surh - Asia Pac J Clin Nutr, 2008 - apjcn.nhri.org.tw
Chemoprevention refers to the use of defined non-toxic chemical regimens to inhibit, reverse
or retard the process of multi-stage carcinogenesis that involves multiple signal transduction …

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF …

YJ Surh, KS Chun, HH Cha, SS Han, YS Keum… - Mutation Research …, 2001 - Elsevier
A wide array of phenolic substances, particularly those present in edible and medicinal
plants, have been reported to possess substantial anticarcinogenic and antimutagenic …

Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention

VS Neergheen, T Bahorun, EW Taylor, LS Jen… - Toxicology, 2010 - Elsevier
Natural phytochemicals derived from dietary sources or medicinal plants have gained
significant recognition in the potential management of several human clinical conditions …

Prevention of human cancer by modulation of chronic inflammatory processes

H Ohshima, H Tazawa, BS Sylla, T Sawa - Mutation Research/Fundamental …, 2005 - Elsevier
Chronic inflammation induced by biological, chemical and physical factors has been
associated with increased risk of human cancer at various sites. Inflammation facilitates the …

Molecular mechanisms and pathways as targets for cancer prevention and progression with dietary compounds

N Nosrati, M Bakovic, G Paliyath - International journal of molecular …, 2017 - mdpi.com
A unique feature of bioactive food ingredients is their broad antioxidant function.
Antioxidants having a wide spectrum of chemical structure and activity beyond basic …

Molecular approaches toward targeted cancer prevention with some food plants and their products: inflammatory and other signal pathways

AR Khuda-Bukhsh, S Das, SK Saha - Nutrition and cancer, 2014 - Taylor & Francis
In recent years, there has been growing interest in cancer prevention by food plants and
their products. Although several plant parts have potentials for chemoprevention and other …

Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review

YJ Surh - Food and Chemical Toxicology, 2002 - Elsevier
A wide variety of phenolic substances derived from spice possess potent antimutagenic and
anticarcinogenic activities. Examples are curcumin, a yellow colouring agent, contained in …

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

MK Shanmugam, JH Lee, EZP Chai, MM Kanchi… - Seminars in cancer …, 2016 - Elsevier
The association between chronic inflammation and cancer development has been well
documented. One of the major obstacles in cancer treatment is the persistent autocrine and …