Identification and pathological characterization of persistent asymptomatic Ebola virus infection in rhesus monkeys
X Zeng, CD Blancett, KA Koistinen… - Nature …, 2017 - nature.com
Ebola virus (EBOV) persistence in asymptomatic humans and Ebola virus disease (EVD)
sequelae have emerged as significant public health concerns since the 2013–2016 EVD …
sequelae have emerged as significant public health concerns since the 2013–2016 EVD …
Humanized mouse model of Ebola virus disease mimics the immune responses in human disease
BH Bird, JR Spengler, AK Chakrabarti… - The Journal of …, 2016 - academic.oup.com
Animal models recapitulating human Ebola virus disease (EVD) are critical for insights into
virus pathogenesis. Ebola virus (EBOV) isolates derived directly from human specimens do …
virus pathogenesis. Ebola virus (EBOV) isolates derived directly from human specimens do …
Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors
J Liu, JC Trefry, AM Babka, CW Schellhase… - Science translational …, 2022 - science.org
Effective therapeutics have been developed against acute Ebola virus disease (EVD) in both
humans and experimentally infected nonhuman primates. However, the risk of viral …
humans and experimentally infected nonhuman primates. However, the risk of viral …
[HTML][HTML] Ebola virus infection associated with transmission from survivors
S Den Boon, BJ Marston, TG Nyenswah… - Emerging Infectious …, 2019 - ncbi.nlm.nih.gov
Ebola virus (EBOV) can persist in immunologically protected body sites in survivors of Ebola
virus disease, creating the potential to initiate new chains of transmission. From the outbreak …
virus disease, creating the potential to initiate new chains of transmission. From the outbreak …
[HTML][HTML] Human adaptation of Ebola virus during the West African outbreak
The 2013–2016 outbreak of Ebola virus (EBOV) in West Africa was the largest recorded. It
began following the cross-species transmission of EBOV from an animal reservoir, most …
began following the cross-species transmission of EBOV from an animal reservoir, most …
Active Ebola virus replication and heterogeneous evolutionary rates in EVD survivors
Following cessation of continuous Ebola virus (EBOV) transmission within Western Africa,
sporadic EBOV disease (EVD) cases continued to re-emerge beyond the viral incubation …
sporadic EBOV disease (EVD) cases continued to re-emerge beyond the viral incubation …
Evolution and spread of Ebola virus in Liberia, 2014–2015
Summary The 2013–present Western African Ebola virus disease (EVD) outbreak is the
largest ever recorded with> 28,000 reported cases. Ebola virus (EBOV) genome sequencing …
largest ever recorded with> 28,000 reported cases. Ebola virus (EBOV) genome sequencing …
[HTML][HTML] Ebola virus localization in the macaque reproductive tract during acute Ebola virus disease
DL Perry, LM Huzella, JG Bernbaum… - The American journal of …, 2018 - Elsevier
Sexual transmission of Ebola virus (EBOV) has been demonstrated more than a year after
recovery from the acute phase of Ebola virus disease (EVD). The mechanisms underlying …
recovery from the acute phase of Ebola virus disease (EVD). The mechanisms underlying …
Ebola virus transmission caused by persistently infected survivors of the 2014–2016 outbreak in West Africa
L Subissi, M Keita, S Mesfin, G Rezza… - The Journal of …, 2018 - academic.oup.com
Abstract The 2014–2016 Ebola virus (EBOV) disease outbreak affected over 29000 people
and left behind the biggest cohort (over 17000 individuals) of Ebola survivors in history …
and left behind the biggest cohort (over 17000 individuals) of Ebola survivors in history …
Successful treatment of Ebola virus–infected cynomolgus macaques with monoclonal antibodies
Ebola virus (EBOV) is considered one of the most aggressive infectious agents and is
capable of causing death in humans and nonhuman primates (NHPs) within days of …
capable of causing death in humans and nonhuman primates (NHPs) within days of …