[PDF][PDF] Repurposing drugs for COVID-19: an approach for treatment in the pandemic

S Khadka, A Yuchi, DB Shrestha… - Altern Ther Health …, 2020 - researchgate.net
Context• Drug repurposing is a relevant approach during the COVID-19 pandemic, because
development of new drugs is time-consuming and costly, and the safety of new drugs is …

Challenges for drug repurposing in the COVID-19 pandemic era

J Sultana, S Crisafulli, F Gabbay, E Lynn… - Frontiers in …, 2020 - frontiersin.org
The coronavirus disease (COVID-19) pandemic has affected an estimated 16 million
persons and caused 0.6 million deaths worldwide by September 2020. The pandemic has …

[PDF][PDF] Role of drug repurposing in current treatment strategies against COVID-19; systemic review

ED Ahire, VN Sonawane, KR Surana - Pharm Reson, 2020 - pharmacy.dypvp.edu.in
COVID-19 has now been affirmedpandemic and novel therapies are immediatelydesirable
as we arrive astageoutside containment. Because COVID-19 is now becoming pandemic …

Drug repurposing for COVID-19: Approaches, challenges and promising candidates

YL Ng, CK Salim, JJH Chu - Pharmacology & therapeutics, 2021 - Elsevier
Traditional drug development and discovery has not kept pace with threats from emerging
and re-emerging diseases such as Ebola virus, MERS-CoV and more recently, SARS-CoV …

Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges

V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …

Combating devastating COVID-19 by drug repurposing

AY Pawar - International Journal of Antimicrobial Agents, 2020 - Elsevier
Despite advances in drug discovery, viral infections remain a major challenge for scientists
across the globe. The recent pandemic of COVID-19 (coronavirus disease 2019), caused by …

Drug repurposing strategies and key challenges for COVID-19 management

S Mule, A Singh, K Greish, A Sahebkar… - Journal of Drug …, 2022 - Taylor & Francis
COVID-19 is a clinical outcome of viral infection emerged due to strain of beta coronavirus
which attacks the type-2 pneumocytes in alveoli via angiotensin-converting enzyme 2 …

Drug repurposing in the COVID-19 era: insights from case studies showing pharmaceutical peculiarities

M Gatti, F De Ponti - Pharmaceutics, 2021 - mdpi.com
COVID-19 may lead to severe respiratory distress syndrome and high risk of death in some
patients. So far (January 2021), only the antiviral remdesivir has been approved, although …

Drug repurposing strategies for COVID-19

SL Senanayake - Future Drug Discovery, 2020 - Taylor & Francis
COVID-19 has now been declared a pandemic and new treatments are urgently needed as
we enter a phase beyond containment. Developing new drugs from scratch is a lengthy …

Drug Repurposing During The COVID-19 Pandemic: Lessons For Expediting Drug Development And Access: Study examines drug repurposing during the COVID-19 …

W Greenblatt, C Gupta, J Kao - Health Affairs, 2023 - healthaffairs.org
The COVID-19 pandemic created a large, sudden unmet public health need for rapid access
to safe and effective treatments. Against this backdrop, policy makers and researchers have …