Emerging therapeutic strategies for Parkinson's disease and future prospects: A 2021 update

NA Gouda, A Elkamhawy, J Cho - Biomedicines, 2022 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder pathologically distinguished by
degeneration of dopaminergic neurons in the substantia nigra pars compacta. Muscle …

[HTML][HTML] Recent developments in the treatment of Parkinson's Disease

TB Stoker, RA Barker - F1000Research, 2020 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a common neurodegenerative disease typified by a movement
disorder consisting of bradykinesia, rest tremor, rigidity, and postural instability. Treatment …

Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs

D Charvin, R Medori, RA Hauser… - Nature Reviews Drug …, 2018 - nature.com
Existing therapeutic strategies for managing Parkinson disease (PD), which focus on
addressing the loss of dopamine and dopaminergic function linked with degeneration of …

Emerging treatment approaches for Parkinson's disease

TB Stoker, KM Torsney, RA Barker - Frontiers in neuroscience, 2018 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease,
manifesting as a characteristic movement disorder with a number of additional non-motor …

Novel targeted therapies for Parkinson's disease

T Ntetsika, PE Papathoma, I Markaki - Molecular Medicine, 2021 - Springer
Parkinson's disease (PD) is the second more common neurodegenerative disease with
increasing incidence worldwide associated to the population ageing. Despite increasing …

Priorities in Parkinson's disease research

WG Meissner, M Frasier, T Gasser, CG Goetz… - Nature reviews Drug …, 2011 - nature.com
The loss of dopaminergic neurons in the substantia nigra pars compacta leads to the
characteristic motor symptoms of Parkinson's disease: bradykinesia, rigidity and resting …

Emerging therapies in Parkinson disease—repurposed drugs and new approaches

A Elkouzi, V Vedam-Mai, RS Eisinger… - Nature Reviews …, 2019 - nature.com
Parkinson disease (PD) treatment options have conventionally focused on dopamine
replacement and provision of symptomatic relief. Current treatments cause undesirable …

Parkinson's disease therapy: what lies ahead?

A Wolff, NU Schumacher, D Pürner… - Journal of Neural …, 2023 - Springer
The worldwide prevalence of Parkinson's disease (PD) has been constantly increasing in
the last decades. With rising life expectancy, a longer disease duration in PD patients is …

Management of Parkinson׳ s disease: Current and future pharmacotherapy

AK Kakkar, N Dahiya - European journal of pharmacology, 2015 - Elsevier
Parkinson׳ s disease (PD) is chronic progressive neurodegenerative disorder characterized
by profound loss of dopaminergic neurons in the nigrostriatal pathway. It is recognized by …

Parkinson's disease: an update on pathogenesis and treatment

T Foltynie, J Kahan - Journal of neurology, 2013 - Springer
The Parkinson's disease research field is a rapidly moving one, as many of the relevant
processes underlying PD neurodegeneration are being deciphered, enabling novel …