In this paper, we discuss the effect of optimal chemotherapy doses on solid tumor during
treatment and cancer recurrence after the end of treatment. First, an optimal control problem …

The mathematical study of the growth and treatment of cancer has been of great interest to
researchers in the recent past as that can help clinical practitioners in adopting new …

There are an increasing number of clinical papers dealing with the continuous delivery of an
anticancer drug to patients. In this paper, two basic theoretical models are presented of …

The mathematical study of cancer received great attention in recent years. The theoretical
and numerical investigations of models employed for studying the growth of cancer cells and …

Cancer chemotherapy with application of one drug is studied. The negative and inhibiting
effect of the tumor on normal cells is taken into account. Under certain assumptions, we …

We investigate some models of a cancer chemotherapy problem where the normal cell
population must be maintained above a lower limit and a measure of the total drug use is …

We investigate a model of a cancer chemotherapy problem where the aim is to minimize the
tumor burden at the end of the treatment period while maintaining a normal cell population …

We consider a mathematical model for the control of the growth of tumor cells which is
formulated as a problem of optimal control theory. It is concerned with chemotherapeutic …

Cancer refers to a set of diseases where normal cells of the body lose mechanisms which
are responsible for controlling their growth and motility. Chemotherapy aims to kill these …

This monograph is a study of optimal control applied to cancer chemotherapy, the treatment
of cancer using drugs that kill cancer cells. The aim is to determine whether current methods …