Background & aims Nitric oxide bioactivity (NO) from endothelial NO synthase (eNOS)
importantly contributes to the maintenance of vascular homeostasis, and reduced eNOS …

Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells
(ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary …

Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and
nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular …

Red blood cells (RBCs) were shown to transport and release nitric oxide (NO) bioactivity
and carry an endothelial NO synthase (eNOS). However, the pathophysiological …

Red blood cells (RBC) have been considered almost exclusively as a transporter of
metabolic gases and nutrients for the tissues. It is an accepted dogma that RBCs take up …

Aim: The aim of the study was to investigate if reduced NO bioavailability and increased
ROS in pre-eclampsia is mediated via RBC-dependent mechanisms. Methods: In this …

Nitric oxide (NO), one of the most important vascular signaling molecules, is primarily
produced by endothelial NO synthase (eNOS). eNOS is tightly regulated by its substrate l …

Nitric oxide (NO), a vascular signaling molecule, is primarily produced by endothelial NO
synthase. Recently, a functional endothelial NO synthase (eNOS) was described in red …

Objective—Mice genetically deficient in endothelial nitric oxide synthase (eNOS−/−) are
hypertensive with lower circulating nitrite levels, indicating the importance of constitutively …

The objective of this study was to determine whether absence of endothelial nitric oxide
synthase (eNOS) affects the expression of cell surface adhesion molecules in endothelial …