We have previously reported that the transplantation of dendritic cells (DCs) brings about
functional recovery after spinal cord injury in mice through the activation of endogenous …

Background Spinal cord injury (SCI) elicits a robust neuroinflammatory reaction which, in
turn, exacerbates the initial mechanical damage. Pivotal players orchestrating this response …

We have previously reported that the anti-inflammatory cytokine IL-10 induces a number of
signaling cascades through the IL-10 receptor in spinal cord neurons in vitro to activate NF …

Following the initial impact, spinal cord injury (SCI) triggers a number of inflammatory
responses which can exacerbate tissue damage in the cord and impair functional recovery …

Abstract Interleukin‐10 (IL‐10) exerts a wide spectrum of regulatory activities in the immune
and inflammatory response. The aim of this study was to investigate the role of endogenous …

We report a treatment for spinal cord injury involving implantation of dendritic cells (DCs),
which act as antigen‐presenting cells in the immune system. The novel mechanisms …

Neural stem cell (NSC) transplantation is a major focus of current research for treatment of
spinal cord injury (SCI). However, it is very important to promote the survival and …

In these studies, we examined the neuroprotective effects of the potent antiinflammatory
cytokine interleukin-10 (IL-10) following spinal cord injury (SCI). Neuroprotection was …

Abstract Interleukin-6 (IL)-6 was originally discovered as a factor that contributes to the
secondary pathological and inflammatory response in the central nervous system (CNS) …

The therapeutic effects of mesenchymal stem cell (MSC) transplantation following spinal
cord injury (SCI) to date have been limited. Therefore, we aimed to enhance the …