Host gene variability and SARS-CoV-2 infection: A review article

I Kaidashev, O Shlykova, O Izmailova, O Torubara… - Heliyon, 2021 - cell.com
SARS-CoV-2 is a global threat that influenced healthcare systems around the world. This
virus caused an infection in humans with different clinical signs and syndromes, severity …

Host polymorphisms and COVID-19 infection

JR Delanghe, MM Speeckaert - Advances in Clinical Chemistry, 2022 - Elsevier
Abstract Coronavirus disease (COVID-19) is an infectious disease caused by a newly
discovered coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) …

Role of genetic variants and host polymorphisms on COVID‐19: From viral entrance mechanisms to immunological reactions

A Adli, M Rahimi, R Khodaie… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by a highly pathogenic emerging
virus, is called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Knowledge …

[HTML][HTML] The relationship between the clinical course of SARS-CoV-2 infections and ACE2 and TMPRSS2 expression and polymorphisms

E Tug, I Fidan, G Bozdayi, F Yildirim… - … in Clinical and …, 2024 - advances.umw.edu.pl
Background. The viral spike (S) protein and host ACE2 and TMPRSS2 genetic variations
may act as a barrier to viral infections or determine susceptibility to severe acute respiratory …

Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection

SMA Hashemi, M Thijssen, SY Hosseini, A Tabarraei… - Archives of …, 2021 - Springer
The SARS-CoV-2 pandemic has become one of the most serious health concerns globally.
Although multiple vaccines have recently been approved for the prevention of coronavirus …

Implications of the Immune Polymorphisms of the Host and the Genetic Variability of SARS-CoV-2 in the Development of COVID-19

J Zepeda-Cervantes, D Martínez-Flores… - Viruses, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current pandemic affecting almost all countries in the world. SARS-CoV-2 is the agent …

ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease

HO Singh, R Choudhari, V Nema, AA Khan - Microbial pathogenesis, 2021 - Elsevier
Background A carboxypeptidase protein called ACE2 is found in many organs. ACE2
protein can play a pivotal role to regulate the pathological changes of several diseases …

COVID-19 and genetic variants of protein involved in the SARS-CoV-2 entry into the host cells

A Latini, E Agolini, A Novelli, P Borgiani, R Giannini… - Genes, 2020 - mdpi.com
The recent global COVID-19 public health emergency is caused by SARS-CoV-2 infections
and can manifest extremely variable clinical symptoms. Host human genetic variability could …

Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes

EA Lopera Maya, A Van der Graaf, P Lanting… - Frontiers in …, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) shows a wide variation in expression and severity of
symptoms, from very mild or no symptoms, to flu-like symptoms, and in more severe cases …

Association between genetic polymorphism, severity, and treatment response among COVID-19 infected Egyptian patients

A Alaa, N Sarhan, MG Lotfy El-Ansary… - Frontiers in …, 2023 - frontiersin.org
Background: The world has been suffering from the Coronavirus Disease-2019 (COVID-19)
pandemic since the end of 2019. The COVID-19-infected patients differ in the severity of the …