Erythropoietin (EPO) is a glycoprotein that is mainly produced in the adult kidney, and it was
initially highlighted for its action on the hematopoietic system. Moreover, EPO is also …

Since the isolation and purification of erythropoietin (EPO) in 1977, the essential role of EPO
for mature red blood cell production has been well established. The cloning of the EPO gene …

Erythropoietin (EPO), a humoral regulator of erythropoiesis and replacement therapy for
selected red blood cell disorders in EPO-deficient patients, has been implicated in a wide …

The process of erythropoiesis in the fetal liver and adult bone marrow is regulated by the
hormone erythropoietin (Epo), which is produced in the kidney at low levels under …

Erythropoietin (EPO) is the crucial cytokine regulator of red blood-cell production. Since the
discovery of EPO in 1985 and the isolation of its cognate receptor four years later, there has …

As the basic function of erythropoietin (Epo) is stimulation of red blood cell production,
systemic overexpression of Epo results in erythrocytosis. The patho‐physiological …

Erythropoietin (EPO) is an evolutionarily conserved hormone well documented for its
erythropoietic role via binding the homodimeric EPO receptor (EPOR) 2. In past decades …

A greatly expanded understanding of the biology of endogenous erythropoietin (EPO) has
emerged since the early 1990s. Originally viewed as the renal hormone dedicated to …

Erythropoietin (EPO) is a 30,400 daltons glycoprotein, consisting of 165 amino acids
produced mainly in the kidney and in the liver and regulating erythrocyitosis. It primarily acts …

In the light of the enthusiasm regarding the use of recombinant human erythropoietin (Epo)
and its analogues for treatment of the anaemias of chronic renal failure and malignancies it …