Adenosine 5′‐monophosphate‐activated protein kinase (AMPK) is a key regulator of
cellular energy homeostasis via modulating metabolism of glucose, lipid, and protein. In …

Adenosine monophosphate (AMP)-activated protein kinase (AMPK) plays a central role in
energy homeostasis and regulation of inflammatory responses. The present study is aimed …

Increasing evidence suggests that microglia are a major cellular contributor to
neuroinflammation. The present study investigated whether Ampelopsin (Amp), a type of …

Neuroinflammation plays a vital role in neurodegenerative conditions. Microglia are a key
component of the neuroinflammatory response. There is a growing interest in developing …

Background Activated microglia interact with astrocytes and neuronal cells to induce
neuroinflammation, which can contribute to the pathogenesis and progression of …

Alzheimer's disease (AD) is a progressively neurodegenerative disease with typical
hallmarks of amyloid β (Aβ) plaque accumulation, neurofibrillary tangle (NFT) formation and …

Amlexanox is an anti-inflammatory and anti-allergic agent used clinically for the treatment of
aphthous ulcers, allergic rhinitis, and asthma. Recent studies have demonstrated that …

Background Microglia-mediated neuroinflammatory response following traumatic brain
injury (TBI) is considered as a vital secondary injury factor, which drives trauma-induced …

Neuroinflammation characterized by microglia activation is the mechanism of the occurrence
and development of various central nervous system diseases. ST2825, as a peptide-mimetic …

Matrix metalloproteinases (MMPs) play a pivotal role in neuroinflammation that is associated
with neurodegenerative diseases. Our group recently reported that MMP-8 mediates …