[HTML][HTML] Impact of the B. 1.1. 7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike
C Graham, J Seow, I Huettner, H Khan, N Kouphou… - bioRxiv, 2021 - ncbi.nlm.nih.gov
The interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the ACE2
receptor on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
receptor on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
Uncovering a conserved vulnerability site in SARS‐CoV‐2 by a human antibody
T Li, H Cai, Y Zhao, Y Li, Y Lai, H Yao… - EMBO Molecular …, 2021 - embopress.org
An essential step for SARS‐CoV‐2 infection is the attachment to the host cell receptor by its
Spike receptor‐binding domain (RBD). Most of the existing RBD‐targeting neutralizing …
Spike receptor‐binding domain (RBD). Most of the existing RBD‐targeting neutralizing …
[HTML][HTML] Increased resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7 to antibody neutralization
The Covid-19 pandemic has ravaged the globe, and its causative agent, SARS-CoV-2,
continues to rage. Prospects of ending this pandemic rest on the development of effective …
continues to rage. Prospects of ending this pandemic rest on the development of effective …
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals
The COVID-19 pandemic is a major threat to global health for which there are only limited
medical countermeasures, and we lack a thorough understanding of mechanisms of …
medical countermeasures, and we lack a thorough understanding of mechanisms of …
Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients
In the absence of approved drugs or vaccines, there is a pressing need to develop tools for
therapy and prevention of Covid-19. Human monoclonal antibodies have very good …
therapy and prevention of Covid-19. Human monoclonal antibodies have very good …
[HTML][HTML] The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies
Monoclonal antibodies against SARS-CoV-2 are a clinically validated therapeutic option
against COVID-19. Because rapidly emerging virus mutants are becoming the next major …
against COVID-19. Because rapidly emerging virus mutants are becoming the next major …
Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic. Rapidly spreading SARS-CoV-2 variants may jeopardize newly …
COVID-19 pandemic. Rapidly spreading SARS-CoV-2 variants may jeopardize newly …
A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope
With the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with increased transmissibility and potential resistance, antibodies and vaccines …
variants with increased transmissibility and potential resistance, antibodies and vaccines …
Structural basis of a human neutralizing antibody specific to the SARS-CoV-2 spike protein receptor-binding domain
M Yang, J Li, Z Huang, H Li, Y Wang, X Wang… - Microbiology …, 2021 - Am Soc Microbiol
The emerging new lineages of severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) have marked a new phase of coronavirus disease 2019 (COVID-19). Understanding …
CoV-2) have marked a new phase of coronavirus disease 2019 (COVID-19). Understanding …