[HTML][HTML] The antigenic anatomy of SARS-CoV-2 receptor binding domain

W Dejnirattisai, D Zhou, HM Ginn, HME Duyvesteyn… - Cell, 2021 - cell.com
Antibodies are crucial to immune protection against SARS-CoV-2, with some in emergency
use as therapeutics. Here, we identify 377 human monoclonal antibodies (mAbs) …

Fruitful neutralizing antibody pipeline brings hope to defeat SARS-Cov-2

A Renn, Y Fu, X Hu, MD Hall, A Simeonov - Trends in pharmacological …, 2020 - cell.com
With the recent spread of severe acute respiratory syndrome coronavirus (SARS-CoV-2) _
infecting> 16 million people worldwide as of 28 July 2020, causing> 650 000 deaths, there …

Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

JL Torres, G Ozorowski, E Andreano… - Proceedings of the …, 2022 - National Acad Sciences
As the coronavirus disease 2019 (COVID-19) pandemic continues, there is a strong need for
highly potent monoclonal antibodies (mAbs) that are resistant against severe acute …

Neutralizing antibodies for the treatment of COVID-19

S Jiang, X Zhang, Y Yang, PJ Hotez, L Du - Nature biomedical …, 2020 - nature.com
Neutralizing antibodies for the treatment of COVID-19 | Nature Biomedical Engineering Skip to
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An update to monoclonal antibody as therapeutic option against COVID-19

P Deb, MMA Molla, KM Saif-Ur-Rahman - Biosafety and Health, 2021 - mednexus.org
With the number of Coronavirus Disease 2019 (COVID-19) cases soaring worldwide and
limited vaccine availability for the general population in most countries, the monoclonal …

Neutralizing antibodies for the prevention and treatment of COVID-19

L Du, Y Yang, X Zhang - Cellular & molecular immunology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) initiates the infection
process by binding to the viral cellular receptor angiotensin-converting enzyme 2 through …

Broadly-neutralizing antibodies against emerging SARS-CoV-2 variants

LB Shrestha, N Tedla, RA Bull - Frontiers in immunology, 2021 - frontiersin.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
have become a major concern in the containment of current pandemic. The variants …

Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …

A perspective on potential antibody-dependent enhancement of SARS-CoV-2

AM Arvin, K Fink, MA Schmid, A Cathcart, R Spreafico… - Nature, 2020 - nature.com
Antibody-dependent enhancement (ADE) of disease is a general concern for the
development of vaccines and antibody therapies because the mechanisms that underlie …