Sex hormone—binding globulin and insulin resistance in African-American women

K Sherif, H Kushner, BE Falkner - Metabolism, 1998 - Elsevier
Sex hormone—binding globulin (SHBG) binds testosterone, determining the level of free,
biologically active hormone, and is a sensitive indicator of androgen status in women. SHBG …

Plasma sex hormone‐binding globulin rather than corticosteroid‐binding globulin is a marker of insulin resistance in obese adult males

JG Lewis, BI Shand, PA Elder… - Diabetes, Obesity and …, 2004 - Wiley Online Library
Aim: Plasma levels of corticosteroid‐binding globulin (CBG) and sex hormone‐binding
globulin (SHBG) may be regulated by insulin. The aim of this study was to test the …

Sex Hormone–Binding Globulin and Risk of Clinical Diabetes in American Black, Hispanic, and Asian/Pacific Islander Postmenopausal Women

BH Chen, K Brennan, A Goto, Y Song, N Aziz… - Clinical …, 2012 - academic.oup.com
BACKGROUND Recent prospective studies have shown a strong inverse association
between sex hormone–binding globulin (SHBG) concentrations and risk of clinical diabetes …

Low sex hormone binding globulin is a potential marker for the metabolic syndrome in different ethnic groups

AH Heald, SG Anderson, F Ivison… - Experimental and …, 2005 - thieme-connect.com
Hepatic sex-hormone binding globulin (SHBG) production is down-regulated by insulin and
low levels reflect insulin resistance. Because insulin resistance is closely related to the …

Relationship of sex hormone binding globulin to overall adiposity and body fat distribution in a biethnic population.

SM Haffner, MS Katz, MP Stern… - International journal of …, 1989 - europepmc.org
Previous data have indicated that decreased sex hormone binding globulin (SHBG) is
associated with increased overall and upper body adiposity and higher levels of glucose …

Serum sex hormone–binding globulin, a determinant of cardiometabolic disorders independent of abdominal obesity and insulin resistance in elderly men and women

A Onat, G Hergenç, A Karabulut, S Albayrak, G Can… - Metabolism, 2007 - Elsevier
Serum sex hormone–binding globulin (SHBG) is related to cardiometabolic disorders; but
whether or not this relationship is purely secondary to hyperinsulinemia and/or obesity …

Level of sex hormone-binding globulin is positively correlated with insulin sensitivity in men with type 2 diabetes

KI Birkeland, KF Hanssen, PA Torjesen… - The journal of clinical …, 1993 - academic.oup.com
The level of sex hormone-binding globulin (SHBG) is associated with glucose metabolism in
nondiabetic women and men, and the finding of low SHBG levels is suggested to be a …

Sex hormone binding globulin and insulin resistance

IR Wallace, MC McKinley, PM Bell… - Clinical …, 2013 - Wiley Online Library
Sex hormone binding globulin (SHBG) is a glycoprotein composed of two 373‐amino‐acid
subunits. The SHBG gene and a promotor region have been identified. The SHBG receptor …

Relationship of sex hormone-binding globulin to lipid, lipoprotein, glucose, and insulin concentrations in postmenopausal women

SM Haffner, JF Dunn, MS Katz - Metabolism, 1992 - Elsevier
Sex hormones play a major role in determining the risk of cardiovascular disease. While
several studies have shown that reduced sex hormone-binding globulin (SHBG) is …

Sex hormone-binding globulin and glucose tolerance in postmenopausal women: The Rancho Bernardo Study

D Goodman-Gruen, E Barrett-Connor - Diabetes Care, 1997 - Am Diabetes Assoc
OBJECTIVE Sex hormone-binding globulin (SHBG) has been shown to be associated with
several diabetes risk factors, including total body fat, central obesity, and hyperinsulinemic …