[HTML][HTML] S100 beta stimulates calcium fluxes in glial and neuronal cells.

SW Barger, LJ Van Eldik - Journal of biological chemistry, 1992 - Elsevier
The glial-derived protein S100 beta can act as a mitogen or a neurotrophic factor,
stimulating proliferation of glial cells or differentiation of immature neurons. We report here …

Neurotrophic protein S100 beta stimulates glial cell proliferation.

RH Selinfreund, SW Barger… - Proceedings of the …, 1991 - National Acad Sciences
Nervous system development involves a coordinated series of events, including regulation
of cell proliferation and differentiation by specific extracellular factors. S100 beta is a …

Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice.

RH Reeves, J Yao, MR Crowley… - Proceedings of the …, 1994 - National Acad Sciences
S100 beta is a calcium-binding protein that is expressed at high levels in brain primarily by
astrocytes. Addition of the disulfide-bonded dimeric form of S100 beta to primary neuronal …

The S100 protein family: history, function, and expression

DB Zimmer, EH Cornwall, A Landar, W Song - Brain research bulletin, 1995 - Elsevier
The S100 family of calcium binding proteins contains approximately 16 members each of
which exhibits a unique pattern of tissue/cell type specific expression. Although the …

Isolation of a new member of the S100 protein family: amino acid sequence, tissue, and subcellular distribution.

JR Glenney Jr, MS Kindy, L Zokas - The Journal of cell biology, 1989 - rupress.org
A low molecular mass protein which we term S100L was isolated from bovine lung. S100L
possesses many of the properties of brain S100 such as self association, Ca++-binding (2 …

S100 protein expression in subpopulations of neurons of rat brain

M Rickmann, JR Wolff - Neuroscience, 1995 - Elsevier
Available data are conflicting as regards the occurrence of Ca2+ and Zn2+ binding S100
proteins in neurons of mammalian brain. Here the localization and expression of S100 was …

Neurite extension and neuronal survival activities of recombinant S100 beta proteins that differ in the content and position of cysteine residues.

F Winningham-Major, JL Staecker, SW Barger… - The Journal of cell …, 1989 - rupress.org
S100 beta produced in Escherichia coli from a synthetic gene (Van Eldik, LJ, JL Staecker,
and F. Winningham-Major. 1988. J. Biol. Chem. 263: 7830-7837) stimulates neurite …

S100B increases proliferation in PC12 neuronal cells and reduces their responsiveness to nerve growth factor via Akt activation

C Arcuri, R Bianchi, F Brozzi, R Donato - Journal of Biological Chemistry, 2005 - ASBMB
S100B is a Ca 2+-modulated protein of the EF-hand type expressed in high abundance in a
restricted set of cell types including certain neuronal populations. S100B has been …

Antisense inhibition of glial S100 beta production results in alterations in cell morphology, cytoskeletal organization, and cell proliferation.

RH Selinfreund, SW Barger, MJ Welsh… - The Journal of cell …, 1990 - rupress.org
The phenotypic effects of selectively decreasing the levels of S100 beta in cultured glial cells
were analyzed. Two separate antisense approaches were utilized for inhibition of S100 beta …

Molecular Mechanisms of Ca2+ Signaling in Neurons Induced by the S100A4 Protein

D Kiryushko, V Novitskaya, V Soroka… - … and cellular biology, 2006 - Taylor & Francis
The S100A4 protein belongs to the S100 family of vertebrate-specific proteins possessing
both intra-and extracellular functions. In the nervous system, high levels of S100A4 …