Tumor cell-mediated neovascularization and lymphangiogenesis contrive tumor progression and cancer metastasis

Z Cao, B Shang, G Zhang, L Miele, FH Sarkar… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Robust neovascularization and lymphangiogenesis have been found in a variety of
aggressive and metastatic tumors. Endothelial sprouting angiogenesis is generally …

Revisiting tumor angiogenesis: vessel co-option, vessel remodeling, and cancer cell-derived vasculature formation

CN Qian, MH Tan, JP Yang, Y Cao - Chinese Journal of Cancer, 2016 - Springer
Tumor growth and metastasis depend on the establishment of tumor vasculature to provide
oxygen, nutrients, and other essential factors. The well-known vascular endothelial growth …

Unraveling the role of angiogenesis in cancer ecosystems

I Zuazo-Gaztelu, O Casanovas - Frontiers in Oncology, 2018 - frontiersin.org
Activation of the tumor and stromal cell-driven angiogenic program is one of the first
requirements in the tumor ecosystem for growth and dissemination. The understanding of …

Molecular mechanisms of tumor vascularization

P Auguste, S Lemiere, F Larrieu-Lahargue… - Critical reviews in …, 2005 - Elsevier
Tumor angiogenesis is a fast growing sub-domain of angiogenesis research and tumor
biology. Basic mechanisms have been unraveled and many key players identified. For many …

Tumour vascularization: sprouting angiogenesis and beyond

F Hillen, AW Griffioen - Cancer and Metastasis Reviews, 2007 - Springer
Tumour angiogenesis is a fast growing domain in tumour biology. Many growth factors and
mechanisms have been unravelled. For almost 30 years, the sprouting of new vessels out of …

Tumor endothelial cells accelerate tumor metastasis

N Maishi, K Hida - Cancer science, 2017 - Wiley Online Library
Tumor metastasis is the main cause of cancer‐related death. Understanding the molecular
mechanisms underlying tumor metastasis is crucial to control this fatal disease. Several …

Tumor angiogenesis: causes, consequences, challenges and opportunities

R Lugano, M Ramachandran, A Dimberg - Cellular and Molecular Life …, 2020 - Springer
Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …

Tumor neovascularization and developments in therapeutics

Y Katayama, J Uchino, Y Chihara, N Tamiya, Y Kaneko… - Cancers, 2019 - mdpi.com
Tumors undergo fast neovascularization to support the rapid proliferation of cancer cells.
Vasculature in tumors, unlike that in wound healing, is immature and affects the tumor …

SnapShot: tumor angiogenesis

RK Jain, P Carmeliet - Cell, 2012 - cell.com
How Do Tumors Recruit Blood Vessels? Blood vessels are indispensible for tumor growth
and metastasis. Hence, tumors exploit multiple avenues to recruit blood vessels …

Targeting tumor vascularization: promising strategies for vascular normalization

R Zheng, F Li, F Li, A Gong - Journal of cancer research and clinical …, 2021 - Springer
Tumor recurrence after the clinical cure of tumor often results from the presence of an
abnormal microenvironment, including an aberrant vasculature. The tumor …