The selective mechanisms for maintaining polymorphism in natural populations has been
the subject of theory, experiments, and review over the past half century. Advances in …

Patterns of variation and evolution at a given site in a genome can be strongly influenced by
the effects of selection at genetically linked sites. In particular, the recombination rates of …

Although models of evolution usually assume that the strength of selection on a trait and the
expression of genetic variation in that trait are independent, whenever the same ecological …

The development of a coherent framework for measuring natural selection was one of the
major advances in evolutionary biology in the 1970s and 1980s. However, for evolution to …

Populations adapt to novel environments in two distinct ways: selection on pre-existing
genetic variation and selection on new mutations. These alternative sources of beneficial …

Ten years ago, Joseph Felsenstein (35) and I (56) both wrote reviews discussing the
maintenance of genetic polymorphisms in heterogeneous environments. I addressed the …

Genetic variation is the raw material upon which selection acts. The majority of
environmental conditions change over time and therefore may result in variable selective …

The maintenance of genetic variation in traits of adaptive significance has been a major
dilemma of evolutionary biology. Considering the pattern of increased genetic variation …

One of the central goals of evolutionary biology is to understand the genetic basis of
adaptive evolution. The availability of nearly complete genome sequences from a variety of …

Levels of genetic differentiation between populations can be highly variable across the
genome, with divergent selection contributing to such heterogeneous genomic divergence …