Background: Mucoadhesive drug delivery is a promising strategy to overcome ocular
biopharmaceutical constraints. Objective and methods: Ciprofloxacin HCl-loaded reverse …

The aim of this study was to prepare natamycin encapsulated lecithin/chitosan
mucoadhesive nanoparticles (NPs) for prolonged ocular application. These NPs were …

The main inconvenience of conventional eye drops is the rapid washout of the drugs due to
nasolacrimal drainage or ophthalmic barriers. The ocular drug bioavailability can be …

Purpose: To characterize nanoparticles produced by self-assembly of oppositely charged
polymers, cationic chitosan (CS), and anionic dextran sulfate (DS), for drug delivery to the …

A fluoroquinolone/glucocorticoid combination for the treatment of bacterial keratitis in the
form of mucoadhesive nanoparticle suspensions was developed to prolong the release and …

The aim of this work is to improve the ocular bioavailability of ciprofloxacin hydrochloride
(CPX) through the preparation of ocular mucoadhesive chitosan (CS)-coated liposomes …

In clinical practices, solution of dorzolamide hydrochloride (DH) and timolol maléate (TM) is
recommended for the treatment of glaucoma. However, low drug-contact time and poor …

Nanoscience and nanotechnology has caused important breakthroughs in different
therapeutic areas. In particular, the application of nanotechnology in ophthalmology has led …

Ciprofloxacin is a commonly used antibiotic for treatment of bacterial conjunctivitis. The
conventional eye drop dosage form is the widely used mode of treatment, but it has low …

The influence of the surface characteristics of colloidal drug carriers in their interaction with
different biological surfaces is becoming increasingly evident. In order to investigate the …