Many formulation strategies have been employed to improve ocular bioavailability of topical
eye drops. The aim of this study was to develop and evaluate a series of solid lipid …

The current research focuses on developing positively charged gelatin nanoparticles loaded
with moxifloxacin for its effective ocular delivery and controlled release in corneal eye layer …

Abstract Solid Lipid Nanoparticles (SLNs) composed of biodegradable physiological lipids
have been widely proposed as efficient drug delivery systems, also for ophthalmic …

Purpose The topically administered drugs through conventional delivery systems have low
bioavailability. Henceforth, the present study was designed to prepare and optimize …

Acyclovir (ACV) is one of the drugs of choice for the treatment of epidermal, ocular or
systemic herpetic infections. Nevertheless, its trans-mucosal limited absorption and the …

The present study involved design of dexamethasone-sodium phosphate (DEX) loaded
mucoadhesive chitosan nanoparticles for topical ocular delivery to improve its precorneal …

This study was conducted to develop timolol maleate (TM)-loaded galactosylated chitosan
(GC) nanoparticles (NPs)(TM-GC-NPs) followed by optimization via a four-level and three …

Context: Chitosan nanoparticles were prepared to encapsulate daptomycin and proposed
as a delivery system of this antibiotic to the eye for the treatment of bacterial endophthalmitis …

The objective of the study was to assess the effect of enhanced mucoadhesion of a cationic
mucoadhesive nanostructured lipid carrier (NLC) on its ocular disposition after topical …

Purpose To assess the potential of chitosan (CS) nanoparticles for ocular drug delivery by
investigating their intraocular retention by γ-scintigraphy and intraocular pressure reduction …