General approach to a spiro indole-3, 1′-naphthalene tetracyclic system: stereoselective pseudo four-component reaction of isatins and cyclic ketones with two …

MN Elinson, AN Vereshchagin, RF Nasybullin… - RSC Advances, 2015 - pubs.rsc.org
A new type of catalytic stereoselective cascade pseudo four-component reaction was
discovered. The simple and facile pseudo four-component reaction of isatins, cyclic ketones …

A novel organocatalytic multi-component reaction: an efficient synthesis of polysubstituted pyrano-fused spirooxindoles

ZN Tisseh, F Ahmadi, M Dabiri, HR Khavasi, A Bazgir - Tetrahedron Letters, 2012 - Elsevier
A practical, simple, and efficient method for the synthesis of pyrano-fused spirooxindoles via
an organocatalytic three-component reaction of isatins, malononitrile, and dialkyl …

Highly enantioselective synthesis of chiral pyranonaphthoquinone‐fused spirooxindoles through organocatalytic three‐component cascade reactions

HW Zhao, B Li, T Tian, W Meng, Z Yang… - European Journal of …, 2015 - Wiley Online Library
In the presence of cinchona‐thiourea organocatalyst C1, the developed organocatalytic
three‐component cascade reaction of isatins, malononitrile, and 2‐hydroxynaphthalene‐1, 4 …

Enantioselective synthesis of 3, 3′-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction

WT Wei, CX Chen, RJ Lu, JJ Wang… - Organic & Biomolecular …, 2012 - pubs.rsc.org
Enantioselective synthesis of 3,3′-dihydropyrryl-spirooxindoles via an organocatalytic
three-component reaction - Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C2OB25629K …

Efficient catalyst-free synthesis of diversified bis (spirooxindoles) via one-pot, three-component reaction

G Khanna, K Aggarwal, JM Khurana - Synthetic Communications, 2016 - Taylor & Francis
ABSTRACT A catalyst-free, one-pot synthesis of bis-spirooxindoles has been carried out by
a three-component reaction of bis-isatins, malononitrile, and various cyclic enolizable …

Triphenylphosphine catalyzed, one-pot, multicomponent synthesis of spirooxindoles

S Riyaz, A Naidu, PK Dubey - Letters in Organic Chemistry, 2012 - ingentaconnect.com
Multicomponent reaction involving isatin (1), malononitrile (2), and dimedone (3), in the
presence of triphenylphosphine as an efficient catalyst in the eco-friendly solvent ethanol …

Tetrabutylammonium‐Bromide‐Promoted Synthesis of Spirooxindoles through Alkyne‐Aldehyde C− C Coupling and 1, 3‐Dipolar Cycloaddition Using Ytterbium …

C Teja, F Rahman Nawaz Khan - ChemistrySelect, 2020 - Wiley Online Library
Tetrabutylammonium‐bromide promoted, ytterbium triflate catalyzed one‐pot domino
synthesis of spirooxindoles is described. The hydration‐condensation of alkyne, 1 aldehyde …

Recent Advances in Green Synthesis of 3, 3′‐Spirooxindoles via Isatin–based One–pot Multicomponent Cascade Reactions in Aqueous Medium

LJ Yan, YC Wang - ChemistrySelect, 2016 - Wiley Online Library
spirooxindoles are important synthetic target compounds and play special role in organic
chemistry because of their extensive biological activities and applications of pharmaceutical …

Multicomponent reaction discovery: three-component synthesis of spirooxindoles

B Liang, S Kalidindi, JA Porco Jr… - Organic letters, 2010 - ACS Publications
The Lewis acid-catalyzed, three-component reaction of isatin and two 1, 3-dicarbonyl
compounds is reported. Reactions proceed with high efficiency under mild reaction …

Efficient synthesis of spiro diheterocycles via multi-component dicyclization reaction

L Wang, P Zhao, S Li, Y Ma, P Zhang… - Organic & Biomolecular …, 2022 - pubs.rsc.org
A facile synthetic protocol for the preparation of spiro diheterocycles from easily available
2′-aminoacetophenones, isocyanates and 1, 4-benzoquinones or quinone monoimines …