Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

The Geoscience paradigm suggests that targeting the aging process could delay or prevent
the risk of multiple major age-related diseases, such as cancer, cardiovascular disease …

Epigenetic clocks have been widely used to predict disease risk in multiple tissues or cells.
Their success as a measure of biological ageing has prompted research on the connection …

Background Epigenetic clocks based on DNA methylation yield high correlations with
chronological age in cross-sectional data. Due to a paucity of longitudinal data, it is not …

Aging is the most important risk factor for major human lifestyle diseases, including cancer,
neurological and cardiometabolic disorders. Due to the complex interplay between genetics …

As a complicated process, aging is characterized by various changes at the cellular,
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …

Background Ageing is one of the principal risk factors for many chronic diseases. However,
there is considerable between-person variation in the rate of ageing and individual …

Abstract Background The Horvath epigenetic clock is widely used. It predicts age quite well
from 353 CpG sites in the DNA methylation profile in unknown samples and has been used …

Aim: To examine the relationships between two epigenetic clocks, aging and exceptional
longevity. Materials & methods: Participants were from three adult cohorts with blood DNA …

All humans age, but how we age—and how fast—differs considerably from person to
person. This deviation between apparent age and chronological age is often referred to as …