Massive high-throughput sequencing techniques allowed the identification of thousands of
noncoding RNAs (ncRNAs) and a plethora of different mRNA processing events occurring in …

Alternative splicing is a highly fine-tuned regulated process and one of the main drivers of
proteomic diversity across eukaryotes. The vast majority of human multi-exon genes is …

Many nascent long non-coding RNAs (lncRNAs) undergo the same maturation steps as pre-
mRNAs of protein-coding genes (PCGs), but they are often poorly spliced. To identify the …

Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In
humans, 90%–95% of multi-exon genes produce alternatively spliced RNA transcripts …

Small nuclear RNAs (snRNAs) are critical components of the spliceosome that catalyze the
splicing of pre-mRNA. snRNAs are each complexed with many proteins to form RNA-protein …

Pre‐mRNA alternative splicing is an important mechanism used to expand protein diversity
in higher eukaryotes, and mutually exclusive splicing is a specific type of alternative splicing …

Alternative splicing greatly expands the transcriptomic and proteomic diversities related to
physiological and developmental processes in higher eukaryotes. Splicing of long …

Alternative splicing of mRNA precursors provides an important means of genetic control and
is a crucial step in the expression of most genes. Alternative splicing markedly affects human …

Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …

Recent improvements in experimental and computational techniques that are used to study
the transcriptome have enabled an unprecedented view of RNA processing, revealing many …