We use state-of-the-art computer-aided drug design (CADD) techniques to identify
prospective inhibitors of the main protease enzyme, 3CLpro of the severe acute respiratory …

Drugs targeting SARS-CoV-2 could have saved millions of lives during the COVID-19
pandemic, and it is now crucial to develop inhibitors of coronavirus replication in preparation …

The rapidly developing pandemic, known as coronavirus disease 2019 (COVID-19) and
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently …

Despite the recent availability of vaccines against the acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the search for inhibitory therapeutic agents has assumed …

Abstract The new Coronavirus (SARS-CoV-2) is the cause of a serious infection in the
respiratory tract called COVID-19. Structures of the main protease of SARS-CoV-2 (M pro) …

We have used a combination of virtual screening (VS) and high-throughput screening (HTS)
techniques to identify novel, non-peptidic small molecule inhibitors against human SARS …

The recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 and
causing the respiratory tract disease COVID-19 has reached worldwide resonance and a …

COVID-19 represents a new potentially life-threatening illness caused by severe acute
respiratory syndrome coronavirus 2 or SARS-CoV-2 pathogen. In 2021, new variants of the …

A novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) has
been the cause of a recent global pandemic. The highly contagious nature of this life …

For the COVID-19 pandemic caused by SARS-CoV-2, there are currently no effective drugs
or vaccines to treat this coronavirus infection. In this study, we focus on the main protease …