L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
The use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication and prevent disease progression to a more severe form. However, the timing of antiviral …
P Sendi, RR Razonable, SB Nelson, A Soriano… - Clinical Microbiology …, 2022 - Elsevier
Background Oral drugs against severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) have received emergency use authorization for the treatment of mild-to-moderate …
EA Meyerowitz, Y Li - Clinical Infectious Diseases, 2024 - academic.oup.com
The goals of coronavirus disease 2019 (COVID-19) antiviral therapy early in the pandemic were to prevent severe disease, hospitalization, and death. As these outcomes have …
R Rosales, BL McGovern, ML Rodriguez, DK Rai… - BioRxiv, 2022 - biorxiv.org
Variants of SARS-CoV-2 have become a major public health concern due to increased transmissibility, and escape from natural immunity, vaccine protection, and monoclonal …
Vaccines and monoclonal antibody treatments to prevent severe coronavirus disease 2019 (COVID-19) illness were available within a year of the pandemic being declared but there …
AC Puhl, TR Lane, F Urbina, S Ekins - Frontiers in Drug Discovery, 2022 - frontiersin.org
While we currently have multiple highly effective vaccines approved for use against SARS- CoV-2 in the USA and other countries, there are far fewer small molecule antivirals …
S Corritori, N Savchuk, CD Pauza - Covid, 2022 - mdpi.com
A complete response to the challenge of COVID-19 requires diagnosis, prevention, and treatment strategies. Until recently, the treatment arm has included largely ineffective, often …
I Karniadakis, N Mazonakis, C Tsioutis… - Infectious Disease …, 2023 - mdpi.com
Vaccines remain the cornerstone of medical prevention and are highly effective in reducing the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the …
DK Brady, AR Gurijala, L Huang, AA Hussain… - The FEBS …, 2024 - Wiley Online Library
Antiviral therapies are integral in the fight against SARS‐CoV‐2 (ie severe acute respiratory syndrome coronavirus 2), the causative agent of COVID‐19. Antiviral therapeutics can be …