The integrin VLA-3 is a cell surface receptor, which binds to fibronectin, laminin, collagen
type I and VI (Takada, Y., EA Wayner, WG Carter, and ME Hemler. 1988. J. Cell. Biochem …

To assess directly the functional role of the integrin VLA-3 (alpha 3 beta 1), we transfected
human alpha 3 cDNA into erythroleukemia (K562) cells and rhabdomyosarcoma (RD) cells …

Cell adhesion to extracellular matrix is mediated by a set of heterodimeric cell surface
receptors called integrins. We have examined the expression of the very late antigens or …

The integrin VLA-2 was previously found to bind to either collagen alone, or collagen plus
laminin, but the mechanism for this cell-specific functional difference was unknown. Here we …

VLA‐4 is a cell surface heterodimer in the integrin superfamily of adhesion receptors. Anti‐
VLA‐4 antibodies inhibited cytolytic T cell activity, with inhibitory activity directed against the …

The capability of the integrin VLA-3 to function as a receptor for collagen (Coll), laminin (Lm),
and fibronectin (Fn) was addressed using both whole cell adhesion assays and ligand …

The integrin family of adhesion receptors includes at least 11 different a subunits and 6
different p subunits which are associated to form at least 14 different a^ heterodimers …

ABSTRACT Various β1 integrins (VLA-2, VLA-3, VLA-4) have been suggested to bind
directly to themselves or to each other, thus mediating cell-cell adhesion. Here we …

Integrins can exist in a range of functional states, depending on the cell type and its state of
activation. Although the mechanism that controls activity is unknown, it has been suggested …

The integrin heterodimer VLA-2, previously known as a collagen receptor, is now shown
also to be a laminin receptor. Adhesion of the human melanoma cell line LOX to laminin was …