The outcome after infection with the human immunodeficiency virus type 1 (HIV-1) is a
complex phenotype determined by interactions among the pathogen, the human host and …

This review aims to provide a summary of current knowledge of host genetic effects on
human immunodeficiency virus (HIV) disease. Mapping of simple single nucleotide …

To extend the understanding of host genetic determinants of HIV-1 control, we performed a
genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study …

The course of Human Immunodeficiency Virus type 1 (HIV) infection is a dynamic interplay in
which both host and viral genetic variation, among other factors, influence disease …

Previous genome-wide association studies (GWAS) of HIV-1–infected populations have
been underpowered to detect common variants with moderate impact on disease outcome …

Research into the effects of host genetics on HIV disease susceptibility and progression, and
on the efficacy and toxicity of drug treatment, occupies a particular position in the landscape …

Allelic variants for the HIV-1 co-receptors chemokine receptor 5 (CCR5) and CCR2, as well
as the ligand for the co-receptor CXCR4, stromal-derived factor (SDF-1), have been …

all-inclusive and objective should benefit this rapidly growing field. Please contact us for
further details.(ji24m@ NIH. gov). The controversy surrounding the effect of specific …

Genetic variation in CC chemokine receptor 5 (CCR5), the major HIV-1 coreceptor, has
been shown to influence HIV-1 transmission and disease progression. However, it is …

Susceptibility to HIV-1 infection and rate of disease progression to AIDS are complex traits
modulated by environmental and genetic factors. Studies on large AIDS cohorts and their …