How should older adults with cancer be evaluated for frailty?

M Huisingh-Scheetz, J Walston - Journal of geriatric oncology, 2017 - Elsevier
Traditionally used as a descriptive term, frailty is now a recognized medical syndrome
identifying individuals with decreased physiologic reserve. Frailty is characterized by …

[HTML][HTML] The prevalence and outcomes of frailty in older cancer patients: a systematic review

C Handforth, A Clegg, C Young, S Simpkins… - Annals of oncology, 2015 - Elsevier
Background Frailty is a state of vulnerability to poor resolution of homeostasis following a
stressor event, such as chemotherapy or cancer surgery. Better knowledge of the …

Frailty and cancer: implications for oncology surgery, medical oncology, and radiation oncology

CG Ethun, MA Bilen, AB Jani, SK Maithel… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

[HTML][HTML] Geriatric assessment is superior to oncologists' clinical judgement in identifying frailty

L Kirkhus, J Šaltytė Benth, S Rostoft… - British journal of …, 2017 - nature.com
Background: Frailty is a syndrome associated with increased vulnerability and an important
predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are …

Frailty and cancer: current perspectives on assessment and monitoring

V Goede - Clinical interventions in aging, 2023 - Taylor & Francis
Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …

Frailty index developed from a cancer-specific geriatric assessment and the association with mortality among older adults with cancer

EJ Guerard, AM Deal, YK Chang, GR Williams… - Journal of the National …, 2017 - jnccn.org
Background: An objective measure is needed to identify frail older adults with cancer who
are at increased risk for poor health outcomes. The primary objective of this study was to …

Are frailty markers useful for predicting treatment toxicity and mortality in older newly diagnosed cancer patients? Results from a prospective pilot study

MTE Puts, J Monette, V Girre, C Pepe… - Critical reviews in …, 2011 - Elsevier
INTRODUCTION: The concept of frailty may be useful to characterize vulnerability. The aim
of this pilot study was to explore the association between frailty/functional status and …

Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients …

L Kirkhus, J Šaltytė Benth, BH Grønberg… - Palliative …, 2019 - journals.sagepub.com
Background: Maintaining quality of life including physical functioning is highly prioritized
among older cancer patients. Geriatric assessment is a recommended approach to identify …

Usefulness of frailty markers in the assessment of the health and functional status of older cancer patients referred for chemotherapy: a pilot study

F Retornaz, J Monette, G Batist… - The Journals of …, 2008 - academic.oup.com
Background. Older cancer patients seen in an oncology clinic seem to be healthier and less
disabled than traditional geriatric patients. Choosing the most sensitive tools to assess their …

[HTML][HTML] Association of frailty and chemotherapy-related adverse outcomes in geriatric patients with cancer: a pilot observational study in Taiwan

YW Ho, WR Tang, SY Chen, SH Lee, JS Chen… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Background: With the rapid growth of the elderly population and the increasing incidence of
cancer, an increasing number of geriatric patients are receiving cancer treatment, making …