Highlights•ESKAPE bacteria are ideal candidates for anti-virulence drugs due to their multi-
drug resistance.•Careful target selection to avoid resistance and maximize anti-virulence …

The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and
mortality worldwide. Carbapenem-resistant Pseudomonas aeruginosa (CRPA) are …

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen, designated by the
World Health Organization as a critical priority for development of new therapeutics due to …

Introduction: Persistent infections caused by the superbug Pseudomonas aeruginosa and its
resistance to multiple antimicrobial agents are huge threats to patients with cystic fibrosis as …

P. aeruginosa is classified as a priority one pathogen by the World Health Organisation, and
new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains …

Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a
comparatively large genome and an impressive genetic capability allowing it to grow in a …

Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis (CF) patients
and causes a wide range of infections among other susceptible populations. Its inherent …

Infections with Pseudomonas aeruginosa have been marked with the highest priority for
surveillance and epidemiological research on the basis of parameters such as incidence …

Resistance of important bacterial pathogens to common antimicrobial therapies and the
emergence of multidrug-resistant bacteria are increasing at an alarming rate and constitute …

As the number of effective antibiotics dwindled, antibiotic resistance (AR) became a pressing
concern. Some Pseudomonas aeruginosa isolates are resistant to all available antibiotics. In …