[HTML][HTML] The anti-inflammatory cytokine response characterized by elevated interleukin-10 is a stronger predictor of severe disease and poor outcomes than the pro …
Objectives Severe coronavirus disease 2019 (COVID-19) is associated with a dysregulated
immune state. While research has focused on the hyperinflammation, little research has …
immune state. While research has focused on the hyperinflammation, little research has …
Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients
MB Azaiz, AB Jemaa, W Sellami, C Romdhani… - Immunobiology, 2022 - Elsevier
The severity of COVID-19 is largely determined by the inflammatory response, a “Cytokine
storm,” that involves both pro-and anti-inflammatory cytokines. In the current study we …
storm,” that involves both pro-and anti-inflammatory cytokines. In the current study we …
Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study
QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …
[HTML][HTML] Clinical value of immune-inflammatory parameters to assess the severity of coronavirus disease 2019
Z Zhu, T Cai, L Fan, K Lou, X Hua, Z Huang… - International Journal of …, 2020 - Elsevier
Objective To explore the clinical value of immune-inflammatory markers to assess the
severity of coronavirus disease 2019 (COVID-19). Methods 127 consecutive hospitalized …
severity of coronavirus disease 2019 (COVID-19). Methods 127 consecutive hospitalized …
[HTML][HTML] Serum IL-23, IL-10, and TNF-α predict in-hospital mortality in COVID-19 patients
Objective The hyperinflammatory response, caused by severe acute respiratory syndrome-2
(SARS-CoV-2), is the most common cause of death in patients with coronavirus disease …
(SARS-CoV-2), is the most common cause of death in patients with coronavirus disease …
[HTML][HTML] Circulating levels of interleukin-6 and interleukin-10, but not tumor necrosis factor-alpha, as potential biomarkers of severity and mortality for COVID-19 …
W Udomsinprasert, J Jittikoon… - Journal of clinical …, 2021 - Springer
Purpose Cytokine storm, an uncontrolled overproduction of inflammatory cytokines
contributing to an aberrant systemic inflammatory response, is a major pathological feature …
contributing to an aberrant systemic inflammatory response, is a major pathological feature …
[HTML][HTML] The role of immunological and clinical biomarkers to predict clinical COVID-19 severity and response to therapy—a prospective longitudinal study
A Copaescu, F James, E Mouhtouris, S Vogrin… - Frontiers in …, 2021 - frontiersin.org
Background The association of pro-inflammatory markers such as interleukin-6 (IL-6) and
other biomarkers with severe coronavirus disease 2019 (COVID-19) is of increasing interest …
other biomarkers with severe coronavirus disease 2019 (COVID-19) is of increasing interest …
Elevated levels of pleiotropic interleukin-6 (IL-6) and interleukin-10 (IL-10) are critically involved with the severity and mortality of COVID-19: an updated longitudinal …
Objectives: Disruption in the natural immune reaction due to SARS-CoV-2 infection can
initiate a potent cytokine storm among COVID-19 patients. An elevated level of IL-6 and IL …
initiate a potent cytokine storm among COVID-19 patients. An elevated level of IL-6 and IL …
[HTML][HTML] Elevated interleukin (IL)-6 as a predictor of disease severity among Covid-19 patients: a prospective cohort study
Background accompanied to the spreading of coronavirus disease 2019 (Covid-19) in the
world, identifying factors related to the severity of the disease is one of the interests of …
world, identifying factors related to the severity of the disease is one of the interests of …
[HTML][HTML] Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy
Objective Several therapies with immune-modulatory functions have been proposed to
reduce the overwhelmed inflammation associated with COVID-19. Here we investigated the …
reduce the overwhelmed inflammation associated with COVID-19. Here we investigated the …