Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines
SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding
domain (RBD) and N-terminal domain (NTD). Here we report the humoral immune response …
domain (RBD) and N-terminal domain (NTD). Here we report the humoral immune response …
SARS-CoV-2 variant Omicron: currently the most complete “escapee” from neutralization by antibodies and vaccines
M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
On December 23, 2021, five groups published their research results of clinical-approved
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …
SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment
D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
[HTML][HTML] Mutational escape from the polyclonal antibody response to SARS-CoV-2 infection is largely shaped by a single class of antibodies
Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals
previously infected with SARS-CoV-2, but the relative contributions of these different …
previously infected with SARS-CoV-2, but the relative contributions of these different …
[HTML][HTML] SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies
Monoclonal antibodies (mAbs) offer a treatment option for individuals with severe COVID-19
and are especially important in high-risk individuals where vaccination is not an option …
and are especially important in high-risk individuals where vaccination is not an option …
[HTML][HTML] Antibody evasion by the P. 1 strain of SARS-CoV-2
Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates …
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates …
A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes
Y Guo, L Huang, G Zhang, Y Yao, H Zhou… - Nature …, 2021 - nature.com
COVID-19 pandemic caused by SARS-CoV-2 constitutes a global public health crisis with
enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can …
enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can …
Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants
Background The receptor-binding domain (RBD) variants of SARS-CoV-2 could impair
antibody-mediated neutralization of the virus by host immunity; thus, prospective …
antibody-mediated neutralization of the virus by host immunity; thus, prospective …
Antibody-mediated neutralization of SARS-CoV-2
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent …
Dear Editor, The ongoing coronavirus disease 2019 (COVID-19) pandemic is a serious
public health crisis, which is caused by severe acute respiratory syndrome coronavirus 2 …
public health crisis, which is caused by severe acute respiratory syndrome coronavirus 2 …