Efficacy of dapagliflozin according to geographic location of patients with heart failure

T Kondo, X Wang, M Yang, PS Jhund… - Journal of the American …, 2023 - jacc.org
Background Because clinical characteristics and prognosis vary by geographic region in
patients with heart failure (HF), the response to treatment may also vary. A previous report …

Effects of dapagliflozin in Asian patients with heart failure and reduced ejection fraction in DAPA-HF

KF Docherty, IS Anand, CE Chiang, VK Chopra… - JACC: Asia, 2022 - jacc.org
Background Patients with heart failure with reduced ejection fraction (HFrEF) in Asia exhibit
many differences from those in other parts of the world. Objectives This study sought to …

Time to clinical benefit of dapagliflozin in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified secondary analysis of the …

M Vaduganathan, BL Claggett, P Jhund… - JAMA …, 2022 - jamanetwork.com
Importance Dapagliflozin was recently shown to reduce cardiovascular death or worsening
heart failure (HF) events in patients with HF with mildly reduced or preserved ejection …

Efficacy and safety of dapagliflozin according to aetiology in heart failure with reduced ejection fraction: insights from the DAPA‐HF trial

JH Butt, JC Nicolau, S Verma… - European journal of …, 2021 - Wiley Online Library
Aims We examined the efficacy and safety of dapagliflozin, compared with placebo,
according to aetiology in patients with heart failure (HF) with reduced ejection fraction …

Dapagliflozin in black and white patients with heart failure across the ejection fraction spectrum

JH Butt, KF Docherty, BL Claggett, AS Desai, JC Fang… - Heart Failure, 2023 - jacc.org
Background Black people have a higher incidence and prevalence of heart failure (HF) than
White people, and once HF has developed, they may have worse outcomes. There is also …

Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes

MC Petrie, S Verma, KF Docherty, SE Inzucchi, I Anand… - Jama, 2020 - jamanetwork.com
Importance Additional treatments are needed for heart failure with reduced ejection fraction
(HFrEF). Sodium-glucose cotransporter 2 (SGLT2) inhibitors may be an effective treatment …

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

PS Jhund, T Kondo, JH Butt, KF Docherty… - Nature medicine, 2022 - nature.com
Whether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a
range of morbidity and mortality outcomes in patients with heart failure regardless of ejection …

Efficacy of dapagliflozin in black versus white patients with heart failure and reduced ejection fraction

KF Docherty, MO Ogunniyi, IS Anand, AS Desai… - Heart Failure, 2022 - jacc.org
Objectives This study sought to investigate the efficacy and safety of dapagliflozin in Black
and White patients with heart failure (HF) with reduced ejection fraction (HFrEF) enrolled in …

Dapagliflozin and New York Heart Association functional class in heart failure with mildly reduced or preserved ejection fraction: the DELIVER trial

JW Ostrominski, M Vaduganathan… - European Journal of …, 2022 - Wiley Online Library
Aims This pre‐specified analysis of the DELIVER trial examined whether clinical benefits of
dapagliflozin in heart failure (HF) with left ventricular ejection fraction (LVEF)> 40% varied by …

Effect of dapagliflozin on total heart failure events in patients with heart failure with mildly reduced or preserved ejection fraction: a prespecified analysis of the …

PS Jhund, BL Claggett, A Talebi, JH Butt… - JAMA …, 2023 - jamanetwork.com
Importance In the Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved
Ejection Fraction Heart Failure (DELIVER) trial, dapagliflozin reduced the risk of time to first …