Dietary flavanols restore hippocampal-dependent memory in older adults with lower diet quality and lower habitual flavanol consumption

AM Brickman, LK Yeung… - Proceedings of the …, 2023 - National Acad Sciences
Dietary flavanols are food constituents found in certain fruits and vegetables that have been
linked to cognitive aging. Previous studies suggested that consumption of dietary flavanols …

Insights into the role of diet and dietary flavanols in cognitive aging: results of a randomized controlled trial

RP Sloan, M Wall, LK Yeung, T Feng, X Feng… - Scientific Reports, 2021 - nature.com
With the world's population aging, age-related memory decline is an impending cognitive
epidemic. Assessing the impact of diet on cognitive aging, we conducted a controlled …

Intake of products containing anthocyanins, flavanols, and flavanones, and cognitive function: a narrative review

SL Gardener, SR Rainey-Smith, M Weinborn… - Frontiers in Aging …, 2021 - frontiersin.org
The purpose of this review is to examine human research studies published within the past 6
years which evaluate the role of anthocyanin, flavanol, and flavanone consumption in …

Benefits in cognitive function, blood pressure, and insulin resistance through cocoa flavanol consumption in elderly subjects with mild cognitive impairment: the Cocoa …

G Desideri, C Kwik-Uribe, D Grassi, S Necozione… - …, 2012 - Am Heart Assoc
Flavanol consumption is favorably associated with cognitive function. We tested the
hypothesis that dietary flavanols might improve cognitive function in subjects with mild …

[HTML][HTML] Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging …

D Mastroiacovo, C Kwik-Uribe, D Grassi… - The American journal of …, 2015 - Elsevier
Background: Recent evidence has indicated that flavanol consumption may have many
health benefits in humans, including improved cognitive activities. Objective: The aim was to …

Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults

AM Brickman, UA Khan, FA Provenzano… - Nature …, 2014 - nature.com
The dentate gyrus (DG) is a region in the hippocampal formation whose function declines in
association with human aging and is therefore considered to be a possible source of age …

Dietary flavanols improve cerebral cortical oxygenation and cognition in healthy adults

G Gratton, SR Weaver, CV Burley, KA Low, EL Maclin… - Scientific reports, 2020 - nature.com
Cocoa flavanols protect humans against vascular disease, as evidenced by improvements
in peripheral endothelial function, likely through nitric oxide signalling. Emerging evidence …

[HTML][HTML] Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk, randomized, double-blind, placebo-controlled trial in …

RJ Kean, DJ Lamport, GF Dodd, JE Freeman… - The American journal of …, 2015 - Elsevier
Background: Research indicates that the chronic consumption of flavonoids is associated
with cognitive benefits in adults with mild cognitive impairment and neurodegenerative …

[HTML][HTML] A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results …

D Vauzour, A Scholey, DJ White, NJ Cohen… - The American journal of …, 2023 - Elsevier
Background There is evidence that both omega-3 long-chain polyunsaturated fatty acids
(PUFAs)(eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) and cocoa …

Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: A bicentric double-blind, randomized …

J Bensalem, S Dudonné, N Etchamendy… - The Journals of …, 2019 - academic.oup.com
Polyphenols are promising nutritional bioactives exhibiting beneficial effect on age-related
cognitive decline. This study evaluated the effect of a polyphenol-rich extract from grape and …