Space curvature-inspired nanoplasmonic sensor for breast cancer extracellular vesicle fingerprinting and machine learning classification

M Kazemzadeh, CL Hisey, A Artuyants… - Biomedical Optics …, 2021 - opg.optica.org
Extracellular vesicles (EVs) are micro and nanoscale lipid-enclosed packages that have
shown potential as liquid biopsy targets for cancer because their structure and contents …

An integrated sample-to-answer SERS platform for multiplex phenotyping of extracellular vesicles

W Lin, L Yuan, Z Gao, G Cai, C Liang, M Fan… - Sensors and Actuators B …, 2023 - Elsevier
Tumor-derived extracellular vesicles (EVs) are emerging as a non-invasive liquid biopsy
marker for cancer diagnosis and treatment monitoring. However, clinical detection …

Enabling sensitive phenotypic profiling of cancer-derived small extracellular vesicles using surface-enhanced Raman spectroscopy nanotags

W Zhang, L Jiang, RJ Diefenbach, DH Campbell… - ACS …, 2020 - ACS Publications
Circulating cancer-derived small extracellular vesicles (EVs) are nanoscale membranous
vesicles shed from cancer cells that are released into surrounding body fluids. Small EVs …

Single particle automated Raman trapping analysis of breast cancer cell-derived extracellular vesicles as cancer biomarkers

J Penders, A Nagelkerke, EM Cunnane, SV Pedersen… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) secreted by cancer cells provide an important insight into cancer
biology and could be leveraged to enhance diagnostics and disease monitoring. This paper …

Hybrid nanoplasmonic porous biomaterial scaffold for liquid biopsy diagnostics using extracellular vesicles

T Rojalin, HJ Koster, J Liu, RR Mizenko, D Tran… - ACS …, 2020 - ACS Publications
For more effective early-stage cancer diagnostics, there is a need to develop sensitive and
specific, non-or minimally invasive, and cost-effective methods for identifying circulating …

Concentric gradient nanoplasmonic sensors for detecting tumor-derived extracellular vesicles

H Feng, S Min, Y Huang, Z Gan, C Liang, WD Li… - Sensors and Actuators B …, 2024 - Elsevier
Quantification of tumor-derived extracellular vesicles (EVs) holds great promise for early
cancer diagnosis and prognosis. Developing a rapid and straightforward EV detection …

Extracellular vesicle identification using label-free surface-enhanced raman spectroscopy: detection and signal analysis strategies

H Shin, D Seo, Y Choi - Molecules, 2020 - mdpi.com
Extracellular vesicles (EVs) have been widely investigated as promising biomarkers for the
liquid biopsy of diseases, owing to their countless roles in biological systems. Furthermore …

Trapping and SERS identification of extracellular vesicles using nanohole arrays

LH Kaufman, T Cooper, GQ Wallace… - … in Biology and …, 2019 - spiedigitallibrary.org
Extracellular vesicles are nanoscale and microscale biological vesicles actively released by
nearly all cell types within the body. These small vesicles have been shown to play …

Detection of breast cancer-specific extracellular vesicles with fiber-optic SPR biosensor

Y Yildizhan, K Driessens, HSK Tsao, R Boiy… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) have attracted great attention as potential biomarkers for cancer
diagnostics. Although several technologies have been developed for EV detection, many of …

Nanostructured‐Based Optical Readouts Interfaced with Machine Learning for Identification of Extracellular Vesicles

C del Real Mata, O Jeanne, M Jalali… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are shed from cancer cells into body fluids, enclosing molecular
information about the underlying disease with the potential for being the target cancer …