BACKGROUND: Many studies have explored the association between soluble interleukin-2
receptor (sIL-2R), cytokines and major depressive disorder (MDD). However, the results of …

Major depressive disorder (MDD) is a debilitating psychiatric disease. The dysregulated
cytokines in depression are assumed due to the hyperactivation of the immune system. Here …

Cumulative meta-analyses are used to evaluate the extent to which further studies are
needed to confirm or refute a hypothesis. We used this approach to assess observational …

Background Major depressive disorder (MDD) is a disabling health problem with a very high
global prevalence and burden. Alteration of inflammatory markers in depression is of …

Background: Abnormal expression of inflammatory cytokines in major depressive disorder
(MDD) suggests the activation of an inflammatory process. The pattern of alterations in …

BACKGROUND: Major depression occurs in 4.4% to 20% of the general population. Studies
suggest that major depression is accompanied by immune dysregulation and activation of …

There is now some evidence that major depression is accompanied by an immune response
with an increased production of pro-inflammatory cytokines, such as interleukin 1 (IL-1), IL-6 …

Recently, it was found that major depression may be accompanied by significant changes in
cell-mediated and humoral immunity. The purpose of this study was to investigate the …

Major depressive disorder (MDD) is a common condition that afflicts the general population
across a broad spectrum of ages and social backgrounds. The inflammatory hypothesis of …

Background More than two-thirds of depressed patients complain of somatic and pain
symptoms, which are frequently regarded as a psychological reaction. Although there is a …