Introduction In immunocompromised patients, acute respiratory failure (ARF) is associated
with high mortality, particularly when invasive mechanical ventilation (IMV) is required. In …

Background We aimed to assess the efficacy of a closed-loop oxygen control in critically ill
patients with moderate to severe acute hypoxemic respiratory failure (AHRF) treated with …

Background Nasal high flow delivered at flow rates higher than 60 L/min in patients with
acute hypoxemic respiratory failure might be associated with improved physiological effects …

Background Optimal noninvasive respiratory support for patients with hypoxemic respiratory
failure should minimize work of breathing without increasing the transpulmonary pressure …

Introduction Critically ill patients with respiratory failure undergoing bronchoscopy have an
increased risk of hypoxaemia-related complications. Previous studies have shown that in …

Background The high-flow nasal cannula (HFNC) delivers up to 60 l/min of humidified
air/oxygen blend at a temperature close to that of the human body. In this study, we tested …

Background The physiological effects of high-flow nasal cannula O 2 therapy (HFNC) have
been evaluated mainly in patients with hypoxemic respiratory failure. In this study, we …

Background High-flow nasal cannula (HFNC) oxygen therapy is being increasingly used to
prevent post-extubation hypoxemic respiratory failure and reintubation. However, evidence …

Background Data on high-flow nasal oxygen after thoracic surgery are limited and confined
to the comparison with low-flow oxygen. Different from low-flow oxygen, Venturi masks …

Background Heart rate, acidosis, consciousness, oxygenation, and respiratory rate
(HACOR) have been used to predict noninvasive ventilation (NIV) failure. However, the …