Several studies have revealed that the hyper-inflammatory response induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease …

Hyper-inflammatory responses induced by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are a major cause of disease severity and death. Predictive prognosis …

BACKGROUND Elevated levels of inflammatory cytokines have been associated with poor
outcomes among COVID-19 patients. It is unknown, however, how these levels compare …

Background The COVID-19 pandemic has led to more than 760,000 deaths worldwide
(correct as of 16th August 2020). Studies suggest a hyperinflammatory response is a major …

Improved understanding and management of COVID-19, a potentially life-threatening
disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward …

Abstract In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the
new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was …

IL-6 is one of the major mediators of the hyper-inflammatory responses with complex
biological functions as it can signal via different modes of action. IL-6 by classical signalling …

Recent studies have provided insights into the pathogenesis of coronavirus disease 2019
(COVID-19),,–. However, the longitudinal immunological correlates of disease outcome …

Background Markedly elevated levels of proinflammatory cytokines and defective type-I
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19) …

Purpose Cytokine storm, an uncontrolled overproduction of inflammatory cytokines
contributing to an aberrant systemic inflammatory response, is a major pathological feature …