B Falkiewicz, W Wiśniowski… - … and Nucleic Acids, 2001 - Taylor & Francis
Full article: SYNTHESIS OF NEW CHIRAL PEPTIDE NUCLEIC ACID (PNA) MONOMERS Skip to Main Content Taylor and Francis Online homepage Taylor and Francis Online …
Y Li, T Jin, K Liu - Nucleosides, Nucleotides and Nucleic Acids, 2001 - Taylor & Francis
The synthesis of a chiral peptide nucleic acid (PNA), which is composed of N-aminoethyl-cis- 4-nucleobase-L-proline units, was described. The chiral PNA monomers containing all four …
T Vilaivan, C Khongdeesameor… - Bioorganic & medicinal …, 2000 - Elsevier
A synthon of d-proline substituted at the 4-position by thymine and at N by a flexible aminoethyl linker, has been used to prepare a novel chiral peptide nucleic acid (cPNA) with …
B Falkiewicz, AS Kołodziejczyk, B Liberek… - Tetrahedron, 2001 - Elsevier
Peptide nucleic acids (PNAs) are intensively studied DNA analogues. We elaborated an efficient procedure for the synthesis of N-, C-protected pseudodipeptides with a reduced …
B Falkiewicz, K Kowalska… - … Nucleotides & Nucleic …, 1999 - Taylor & Francis
The aim of this work was the preparation of four new peptide nucleic acid (PNA) monomer backbone by reductive animation of Nα-Boc-protected chiral amino aldehydes, derived from …
T Sugiyama, A Kittaka - Molecules, 2012 - mdpi.com
A peptide nucleic acid (PNA) is a synthetic nucleic acid mimic in which the sugar-phosphate backbone is replaced by a peptide backbone. PNAs hybridize to complementary DNA and …
S Sforza, T Tedeschi, R Corradini… - European Journal of …, 2003 - Wiley Online Library
The solid‐phase synthesis of chiral peptide nucleic acids (PNAs) usually results in partial epimerization of the products, since the α‐nitrogen atom of the amino acid is involved in an …
BP Gangamani, VA Kumar, KN Ganesh - Tetrahedron, 1999 - Elsevier
This paper describes chemical synthesis of prolyl PNAs which are a class of conformationally constrained chiral PNA analogues. The monomers are derived from …