ABSTRACT A multiplex PCR assay that detects the four commonest causes of viral
meningitis and encephalitis in the United Kingdom (herpes simplex virus [HSV] type 1 [HSV …

ABSTRACT A sensitive multiplex PCR assay for single-tube amplification that detects
simultaneous herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) …

Laboratory findings for cerebrospinal fluid (CSF) specimens were correlated with clinical
presentations and histories in 55 cases of encephalitis or meningitis due to herpes simplex …

Until recently, the laboratory diagnosis of central nervous system (CNS) infections with
herpes simplex virus (HSV) has been limited by poor sensitivity and/or specificity. We …

Most patients with herpes simplex virus (HSV) central nervous system (CNS) infection have
abnormal cerebrospinal fluid (CSF) indices. Therefore, we implemented screening criteria …

The laboratory diagnostic strategy used to determine the etiology of encephalitis in 203
patients is reported. An etiological diagnosis was made by first-line laboratory testing for 111 …

ABSTRACT A conventional multiplex PCR assay that detects herpes simplex virus type 1
(HSV-1), HSV-2, varicella-zoster virus, and enteroviruses for the diagnosis of central …

In this study we have devised a simple and robust PCR strategy to detect a wide range of
viruses, bacteria, and parasites, all of which are capable of causing aseptic meningitis and …

The diagnosis of a wide range of different neurological syndromes was established by a
reverse transcription multiplex PCR assay. The presence of enterovirus and herpesviruses …

Amplification of viral nucleic acids from the cerebrospinal fluid (CSF) has considerably
improved the diagnosis of several acute, subacute and chronic viral infections of the nervous …