Misincorporation of d-tyrosine (d-Tyr) into cellular proteins due to mischarging of tRNATyr
with d-Tyr by tyrosyl-tRNA synthetase inhibits growth and biofilm formation of Bacillus …

The Bacillus subtilis tyrS gene, which encodes tyrosyl-tRNA synthetase (TyrTS), was
isolated, and its nucleotide sequence was determined. The cloned gene was shown to …

Bacteria produce d-amino acids for incorporation into the peptidoglycan and certain
nonribosomally produced peptides. However, d-amino acids are toxic if mischarged on …

In this review, we summarize progress on the regulation of the aminoacyl-tRNA synthetase
genes in Bacillus subtilis. Most of the genes encoding this set enzymes in B subtilis are …

The tyrS genes from Escherichia coli and Bacillus stearothermophilus were toxic to E. coli
when they were carried by plasmids with very high copy numbers (pEMBL8 and pEMBL9) …

The tyrosyl-tRNA synthetase gene (tyrZ) from Thiobacillus ferrooxidans, an acidophilic,
autotrophic, gram-negative bacterium that participates in bioleaching of minerals, was …

Sequence comparisons have been combined with mutational and kinetic analyses to
elucidate how the catalytic mechanism of Bacillus stearothermophilus tyrosyl-tRNA …

The Bacillus subtilis tyrS gene belongs to the T box family of aminoacyl‐tRNA synthetase
and amino acid biosynthesis genes, which are regulated by a common mechanism of …

Bacterial tyrosyl‐tRNA synthetases occur in two large subfamilies, TyrRS and TyrRZ, that
possess about 25% amino acid identity. Their amino‐terminal region, the active site domain …

An efficient system was developed for the co-expression of a yeast tRNATyr/tyrosyl-tRNA
synthetase(TyrRS) pair in Escherichia coli. Analysis of suppression patterns using several …