Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature

L Weber, A Torres, O Realini, MJ Bendek… - International Journal of …, 2024 - mdpi.com
Despite the understanding of the coronavirus disease-19 (COVID-19), the role of salivary
extracellular vesicles (sEVs) in COVID-19 remains unclear. Exploring the proteomic cargo of …

Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis

E Moreno, S Ciordia, SM Fátima, D Jiménez… - Clinical Proteomics, 2024 - Springer
Background Information on the microbiome's human pathways and active members that can
affect SARS-CoV-2 susceptibility and pathogenesis in the salivary proteome is very scarce …

COVID-19 Salivary Protein Profile: Unravelling Molecular Aspects of SARS-CoV-2 Infection

E Esteves, VM Mendes, B Manadas, R Lopes… - Journal of Clinical …, 2022 - mdpi.com
COVID-19 is the most impacting global pandemic of all time, with over 600 million infected
and 6.5 million deaths worldwide, in addition to an unprecedented economic impact …

The proteomic characteristics of airway mucus from critical ill COVID-19 patients

Z Zhang, T Wang, F Liu, A Zhu, G Gu, J Luo, J Xu… - Life Sciences, 2021 - Elsevier
Background The pandemic of the coronavirus disease 2019 (COVID-19) has brought a
global public health crisis. However, the pathogenesis underlying COVID-19 are barely …

Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis

EM del Olmo, S Ciordia, FM Santos, D Jiménez… - Authorea …, 2023 - techrxiv.org
The information on the microbiome's human pathways and active members that can affect
SARS-CoV-2 susceptibility and pathogenesis in the salivary proteome is very scarce. Here …

Proteomics of serum-derived extracellular vesicles are associated with the severity and different clinical profiles of patients with COVID-19: An exploratory secondary …

AFP Leme, S Yokoo, AGC Normando, JVS Ormonde… - Cytotherapy, 2024 - Elsevier
Background aims Coronavirus disease 2019 (COVID-19) is characterized by a broad
spectrum of clinical manifestations with the potential to progress to multiple organ …

Noninvasive nasopharyngeal proteomics of COVID-19 patient identify abnormalities related to complement and coagulation cascade and mucosal immune system

MA Ayass, W Cao, J Zhang, J Dai, K Zhu, T Tripathi… - Plos one, 2022 - journals.plos.org
Serum or plasma have been the primary focus of proteomics studies for COVID-19 to identity
biomarkers and potential drug targets. The nasal mucosal environment which consists of …

Sera proteomic features of active and recovered COVID-19 patients: potential diagnostic and prognostic biomarkers

L Leng, M Li, W Li, D Mou, G Liu, J Ma… - Signal transduction and …, 2021 - nature.com
The early diagnosis and prognosis of COVID-19 remain major challenges. At present, there
are few studies focusing on the changes of sera proteome between active and recovered …

Proteomic profiling of single extracellular vesicles reveals colocalization of SARS-CoV-2 with a CD81/integrin-rich EV subpopulation in sputum from COVID-19 severe …

R Sun, Y Cai, Y Zhou, G Bai, A Zhu, P Kong… - Frontiers in …, 2023 - frontiersin.org
Background The global outbreak of COVID-19, and the limited availability of clinical
treatments, forced researchers around the world to search for the pathogenesis and …

Proteomic profile of procoagulant extracellular vesicles reflects complement system activation and platelet hyperreactivity of patients with severe COVID-19

ECS Moraes, R Martins-Gonçalves, LR Silva… - Frontiers in Cellular …, 2022 - frontiersin.org
Background Extracellular vesicles (EVs) are a valuable source of biomarkers and display
the pathophysiological status of various diseases. In COVID-19, EVs have been explored in …