Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …

Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …

Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …

Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …

Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

Background While numerous studies have documented the power of new generation
epigenetic clocks to predict morbidity and mortality, research regarding the causes of …

Different psychiatric disorders as well as exposure to adverse life events have individually
been associated with multiple age-related diseases and mortality. Age acceleration in …

Accelerated epigenetic aging relative to chronological age has been found to be associated
with higher risk of mortality in adults. However, little is known about whether and how in …

Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …

Background Longitudinal studies are needed to clarify whether early adversities are
associated with advanced methylation age or if they actually accelerate methylation aging …