Recent evidence shows that the renin‐angiotensin system is a crucial player in
atherosclerotic processes. The regulation of arterial blood pressure was considered from its …

Inflammation is a key mechanism in the initiation, progression, and clinical sequelae of
cardiovascular diseases (CVDs), including atherosclerosis, nephropathy, and …

Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized
by chronic inflammatory response. Although hypertension is known to be one of the most …

The renin angiotensin system was demonstrated to play a significant role in the genesis of
hypertension and regulation of vascular tone over 100 years ago. The early investigations …

Numerous clinical and laboratory data are now available supporting the hypothesis that the
renin–angiotensin system is mechanistically relevant in the pathogenesis of atherosclerosis …

Clinical and experimental evidence suggests that the pathways by which hypertension and
dyslipidemia lead to vascular disease may overlap and that angiotensin II (Ang II) is involved …

Abstract Purpose of Review Mechanisms facilitating progression of hypertension via cross
stimulation of the renin-angiotensin system (RAS) and inflammation have been proposed …

Angiotensin (Ang) II, the main effector of the renin–angiotensin system (RAS), is one of the
major mediators of vascular remodeling in hypertension. Besides being a potent vasoactive …

It is now well established that vascular inflammation is an independent risk factor for the
development of atherosclerosis. In otherwise healthy patients, chronic elevations of …

Multiple data suggest that the renin-angiotensin system contributes to the pathogenesis of
atherosclerosis. The atherogenic effect of the renin-angiotensin system can only in part be …