Deregulation of SOX9 in esophageal cancer has been reported. However, the regulatory
mechanisms underlying SOX9 during esophageal squamous cell carcinoma (ESCC) …

The transcriptional network of the SRY (sex determining region Y)‐box 17 (SOX17) and the
prognostic impact of SOX17 protein expression in human cancers remain largely unclear. In …

As a transcription factor critical for embryonic and adult stem cell self-renewal and function,
SOX2 gene amplification has been recognized as a driving factor for various cancers …

Background Novel therapies tailored to the molecular composition of esophageal squamous
cell carcinoma (ESCC) are needed to improve patient survival. We investigated the …

The transcription factor SOX 2 is essential for the maintenance of embryonic stem cells and
normal development of the esophagus. Our previous study revealed that the SOX2 gene is …

Gastric cancer remains one of the leading causes of global cancer mortality due to therapy
resistance, with Helicobacter pylori (H. pylori) infection being a major risk factor. In this study …

Background Esophageal squamous cell carcinoma (ESCC) is the major histological type of
esophageal cancer in developing countries. The prognosis and survival rate of ESCC are …

Objective Many cancers engage embryonic genes for rapid growth and evading the immune
system. SOX9 has been upregulated in many tumours, yet the role of SOX9 in mediating …

Purpose: By using cDNA microarray analysis, we identified a transcriptional factor, SOX6,
was frequently downregulated in esophageal squamous cell carcinoma (ESCC). The aim of …

High levels of SOX4 expression have been found in a variety of human cancers, such as
lung, brain and breast cancers. However, the expression of SOX4 in gastric tissues remains …